首页> 外文OA文献 >Influence of exogenous glutathione (GSH), as stressfactor, on the activity of lysosome enzymes in some organs of mice
【2h】

Influence of exogenous glutathione (GSH), as stressfactor, on the activity of lysosome enzymes in some organs of mice

机译:外源性谷胱甘肽(GSH)作为应激因子对小鼠某些器官溶酶体酶活性的影响

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务,本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文,但由于OA文献来源多样且变更频繁,仍可能出现获取不到、文献不完整或与标题不符等情况,如果获取不到我们将提供退款服务。请知悉。

摘要

The studies were carried on 30 random 8-week old Swiss male mice. The mice of I group received peritoneally 100 μg/g b.w. of reduced glutathione (GSH) in 250 μl 0.9% NaCl , II group 200 μg/ g of GSH in 250 μl 0.9% NaCl and mice of III control group received 250 μl of 0.9 % NaCl. In the lysosomal fraction of the liver, kidney and the skeletal muscle the activity of nine lysosomal enzymes were estimated. GSH injections caused in the liver a statistically confirmed increase of activity of estimated hydrolases, only the activity LL decreased significantly and NAGL did not change. After injection of both GSH doses increased significantly the activity LAP, Cat. D and L, AP, BGAL, BGLU and NAGL in the kidney. After injection 200 μg/g of GSH increased significantly activity AAP but an activity EL and LL decreased. In the skeletal muscle was observed a statistically confirmed increase of AP, LL, BGAL and NAGL activity, only the BGLU and Cat. D and L (after 100 μg/g dose) activity decreased.
机译:研究是对30只随机的8周龄的瑞士雄性小鼠进行的。 I组的小鼠腹膜接受100μg/ g体重。在250μl0.9%NaCl中还原谷胱甘肽(GSH)的含量,II组在250μl0.9%NaCl中的200μg/ g GSH,III对照组的小鼠接受250μl0.9%NaCl。在肝,肾和骨骼肌的溶酶体部分中,估计了九种溶酶体酶的活性。肝脏中GSH注射引起的估计水解酶活性得到统计学证实,只有LL活性显着降低,NAGL不变。两种GSH剂量注射后,LAP的活性均显着增加。肾脏中的D和L,AP,BGAL,BGLU和NAGL。注射200μg/ g GSH后,AAP活性显着增加,但EL和LL活性降低。在骨骼肌中观察到统计学上证实的AP,LL,BGAL和NAGL活性增加,只有BGLU和Cat升高。 D和L(100μg/ g剂量后)活性降低。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号