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Achilles Tendinopathy: Current Concepts about the Basic Science and Clinical Treatments

机译:Achilles肌腱病:目前关于基础科学和临床治疗的概念

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摘要

Achilles tendinopathy is one of the most frequently ankle and foot overuse injuries, which is a clinical syndrome characterized by the combination of pain, swelling, and impaired performance. The two main categories of Achilles tendinopathy are classified according to anatomical location and broadly include insertional and noninsertional tendinopathy. The etiology of Achilles tendinopathy is multifactorial including both intrinsic and extrinsic factors. Failed healing response and degenerative changes were found in the tendon. The failed healing response includes three different and continuous stages (reactive tendinopathy, tendon disrepair, and degenerative tendinopathy). The histological studies have demonstrated an increased number of tenocytes and concentration of glycosaminoglycans in the ground substance, disorganization and fragmentation of the collagen, and neovascularization. There are variable conservative and surgical treatment options for Achilles tendinopathy. However, there has not been a gold standard of these treatments because of the controversial clinical results between various studies. In the future, new level I researches will be needed to prove the effect of these treatment options.
机译:Achilles肌腱病是最常见的脚踝和脚过度使用伤害之一,这是一种临床综合征,其特征在于疼痛,肿胀和性能受损的组合。两种主要类别的阿基里斯腱鞘根据解剖学定位分类,并且广泛地包括插入和非栖息的肌腱病。 Achilles腱鞘病的病因是多重型,包括内在和外在因子。在肌腱中发现了愈合响应失败和退行性变化。愈合失败的愈合失败包括三个不同和连续的阶段(反应性肌腱病,肌腱失挡和退行性肌腱病变)。组织学研究已经证明了地下物质,胶原蛋白的紊乱和碎裂中的糖蛋白酶蛋白酶蛋白酶体的数量增加,胶原蛋白酶和新血管形成。 Achilles肌腱病患者有可变保守和外科治疗选择。然而,由于各种研究之间存在有争议的临床结果,这些治疗的黄金标准是缺陷的。在未来,将需要新的水平,以证明这些治疗方案的效果。

著录项

  • 作者

    Hong-Yun Li; Ying-Hui Hua;

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  • 年度 2016
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  • 原文格式 PDF
  • 正文语种 eng
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