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Distinguishing therapeutic monoclonal antibodies from patient monoclonal proteins by electrospray time-of-flight mass spectrometry

机译：通过电喷雾飞行时间质谱法将治疗单克隆抗体与患者单克隆蛋白质中的区分

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Jordyn A. Moore; Catherine S. Rollo; Christiaan W. Sies; Richard I. King;
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1. Electrospray Ionization Quadrupole Ion-Mobility Time-of-Flight Mass Spectrometry as a Tool to Distinguish the Lot-to-Lot Heterogeneity in N-Glycosylation Profile of the Therapeutic Monoclonal Antibody Trastuzumab [J] . Carola W. N. Damen, Weibin Chen, Asish B. Chakraborty, Journal of the American Society for Mass Spectrometry . 2009,第11期

机译：电喷雾电离四极杆离子淌度飞行时间质谱法可用于区分治疗性单克隆抗体曲妥珠单抗的N-糖基化谱中的批次间异质性
2. Determination of N-glycosylation sites and site heterogeneity in a monoclonal antibody by electrospray quadrupole ion-mobility time-of-flight mass spectrometry [J] . Olivova P, Chen WB, Chakraborty AB, Rapid Communications in Mass Spectrometry: RCM . 2008,第1期

机译：电喷雾四极杆离子迁移飞行时间质谱法测定单克隆抗体中的N-糖基化位点和位点异质性
3. Structural characterization of a recombinant monoclonal antibody by electrospray time-of-flight mass spectrometry. [J] . Wang L, Amphlett G, Lambert JM, Pharmaceutical research . 2005,第8期

机译：通过电喷雾飞行时间质谱对重组单克隆抗体进行结构表征。
4. High Resolution Native Mass Spectrometry allows rapid characterization of therapeutic monoclonal antibodies: from PTM to antibody-drug conjugates analysis. [C] . Sara Rosati, Albert J.R. Heck International Mass Spectrometry Conference . 2014

机译：高分辨率本地质谱允许快速表征治疗单克隆抗体：从PTM到抗体 - 药物缀合物分析。
5. Understanding physical and chemical stability of proteins in solution: Relevance to therapeutic protein and monoclonal antibody formulations [D] . Thirumangalathu, Renuka 2007

机译：了解溶液中蛋白质的物理和化学稳定性：与治疗性蛋白质和单克隆抗体制剂的相关性
6. P135-T Structural Characterization of a Recombinant Monoclonal Antibody by Electrospray Ion-Mobility Time-of-Flight Mass Spectrometry [O] . W. Chen, P. Olivova, A. B. Chakraborty, 2007

机译：电喷雾离子迁移飞行时间质谱的重组单克隆抗体的P135-T结构表征
7. Electrospray Ionization Quadrupole Ion-Mobility Time-of-Flight Mass Spectrometry as a Tool to Distinguish the Lot-to-Lot Heterogeneity in N-Glycosylation Profile of the Therapeutic Monoclonal Antibody Trastuzumab [O] . Damen Carola W.N., Chen Weibin, Chakraborty Asish B., 2009

机译：电喷雾电离四极杆离子淌度飞行时间质谱法可用于区分治疗性单克隆抗体曲妥珠单抗的N-糖基化谱中批次之间的异质性

Distinguishing therapeutic monoclonal antibodies from patient monoclonal proteins by electrospray time-of-flight mass spectrometry

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