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Silencing or inhibition of H3K79 methyltransferase DOT1L induces cell cycle arrest by epigenetically modulating c-Myc expression in colorectal cancer

机译：H3K79甲基转移酶DOT1L的沉默或抑制通过在结肠直肠癌中表现出C-MYC表达来诱导细胞循环滞留

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Liqun Yang; Qian Lei; Lin Li; Jie Yang; Zhen Dong; Hongjuan Cui;
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1. Inhibition of DNA methyltransferase induces G2 cell cycle arrest and apoptosis in human colorectal cancer cells via inhibition of JAK2/STAT3/STAT5 signalling [J] . Hua Xiong, Zhao-Fei Chen, Qin-Chuan Liang, Journal of cellular and molecular medicine. . 2009,第9b期

机译：抑制DNA甲基转移酶通过抑制JAK2 / STAT3 / STAT5信号传导诱导大肠癌细胞G2细胞周期停滞和凋亡
2. NUP37 silencing induces inhibition of cell proliferation, G1 phase cell cycle arrest and apoptosis in non-small cell lung cancer cells [J] . Huang Lianglong, Wang Tao, Wang Fumu, Pathology Research and Practice . 2020,第3期

机译：NUP37沉默诱导非小细胞肺癌细胞中细胞增殖的抑制，G1相细胞周期停滞和凋亡
3. IARS2 silencing induces non-small cell lung cancer cells proliferation inhibition, cell cycle arrest and promotes cell apoptosis [J] . Yin J., Liu W., Li R., Neoplasma: Journal of Experimental and Clinical Oncology . 2016,第1期

机译：IARS2沉默诱导非小细胞肺癌细胞增殖抑制，细胞周期阻滞并促进细胞凋亡
4. Sensitization of human colorectal cancer cells to paclitaxel- induced apoptosis by inhibition of MEK/ERK pathway is caspase-4 dependent [C] . NIZAR M. MHAIDAT, SAIED A. JARADAT, ABDULHAMEED GHABKARI Recent researches in modern medicine . 2011

机译：通过抑制MEK / ERK途径使大肠癌细胞对紫杉醇诱导的细胞凋亡的敏感性取决于caspase-4
5. A comprehensive analysis of Dot1L action in mouse embryonic stem cells: A unique histone methyltransferase required for cell cycle progression and gene expression. [D] . Barry, Evan. 2009

机译：小鼠胚胎干细胞中Dot1L作用的全面分析：细胞周期进程和基因表达所需的独特组蛋白甲基转移酶。
6. Silencing or inhibition of H3K79 methyltransferase DOT1L induces cell cycle arrest by epigenetically modulating c-Myc expression in colorectal cancer [O] . Liqun Yang, Qian Lei, Lin Li, 2019

机译：沉默或抑制H3K79甲基转移酶DOT1L通过表观遗传调节结直肠癌中c-Myc表达诱导细胞周期停滞
7. Inhibition of DNA methyltransferase induces G2 cell cycle arrest and apoptosis in human colorectal cancer cells via inhibition of JAK2/STAT3/STAT5 signalling [O] . Hua Xiong, Zhao-Fei Chen, Qin-Chuan Liang, 2009

机译：DNA甲基转移酶对DNA甲基转移酶的抑制通过JAK2 / Stat3 / Stat5信号传导抑制人结肠直肠癌细胞中的G2细胞循环滞留和凋亡

Silencing or inhibition of H3K79 methyltransferase DOT1L induces cell cycle arrest by epigenetically modulating c-Myc expression in colorectal cancer

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