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Analogs of the novel phytohormone, strigolactone, trigger apoptosis and synergize with PARP inhibitors by inducing DNA damage and inhibiting DNA repair

机译：通过诱导DNA损伤和抑制DNA修复，新型植物激素，滴虫，触发凋亡和与PARP抑制剂的协同作用

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Michael P. Croglio; Jefferson M. Haake; Colin P. Ryan; Victor S. Wang; Jennifer Lapier; Jamie P. Schlarbaum; Yaron Dayani; Emma Artuso; Cristina Prandi; Hinanit Koltai; Keli Agama; Yves Pommier; Yu Chen; Lucas Tricoli; Jeannine R. LaRocque; Christopher Albanese; Ronit I. Yarden;
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1. Design, Synthesis, and Evaluation of New Quinazolinone Derivatives that Inhibit Bloom Syndrome Protein (BLM) Helicase, Trigger DNA Damage at the Telomere Region, and Synergize with PARP Inhibitors [J] . Wang Chen-Xi, Zhang Zi-Lin, Yin Qi-Kun, Journal of Medicinal Chemistry . 2020,第17期

机译：抑制盛开综合征蛋白（BLM）螺旋酶，触发端粒区域触发DNA损伤的新喹唑啉酮衍生物的设计，合成和评价，并用PARP抑制剂进行协同
2. Palbociclib induces DNA damage and inhibits DNA repair to induce cellular senescence and apoptosis in oral squamous cell carcinoma [J] . Tong-Hong Wang, Chin-Chuan Chen, Yann-Lii Leu, Journal of the Formosan Medical Association =: Taiwan yi zhi . 2021,第9期

机译：Palbociclib诱导DNA损伤并抑制DNA修复，以诱导口腔鳞状细胞癌中的细胞衰老和凋亡
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4. PENTOXIFYLLINE INHIBITS THE IRRADIATION INDUCED G_2/M BLOCK AND ALTERS DNA SYNTHESIS IN P53 MUTANT AND REPAIR DEFICIENT CELLS [C] . NATO advanced research workshop on fundamentals for the assessment of risks from environmental radiation . 1999

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5. Loss of ATRX Confers DNA Repair Defects and PARP Inhibitor Sensitivity in Glioma [D] . Garbarino, Jennifer Mary. 2021

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6. Analogs of the novel phytohormone strigolactone trigger apoptosis and synergize with PARP inhibitors by inducing DNA damage and inhibiting DNA repair [O] . Michael P. Croglio, Jefferson M. Haake, Colin P. Ryan, 2016

机译：新型植物激素strigolactone的类似物通过诱导DNA损伤和抑制DNA修复来触发细胞凋亡并与PARP抑制剂协同作用
7. Design, Synthesis and Evaluation of New Quinazolinone Derivatives that Inhibit Bloom Syndrome Protein (BLM) Helicase, Trigger DNA Damage at the Telomere Region, and Synergize with PARP Inhibitors [O] . -1

机译：抑制盛开综合征蛋白（BLM）螺旋酶，触发端粒区域触发DNA损伤的新喹唑啉酮衍生物的设计，合成和评价，并用PARP抑制剂进行促进

Analogs of the novel phytohormone, strigolactone, trigger apoptosis and synergize with PARP inhibitors by inducing DNA damage and inhibiting DNA repair

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