Effect of Refractive Status and Axial Length on Peripapillary Retinal Nerve Fibre Layer Thickness: An Analysis Using 3D OCT

摘要

Background: Accurate measurement of retinal nerve fiber layer(RNFL) is now possible with the high resolution optical coherencetomography (OCT). Effect of refractive status of the eye on RNFLthickness may be relevant in the diagnosis of glaucoma and otheroptic nerve diseases.Aim: To assess the RNFL thickness and compare its correlationwith refractive status and axial length of the eye.Material and Methods: Three hundred eyes of 150 patientswere included in this study, who underwent RNFL analysis usingTOPCON 3D OCT 2000. Analysis of variance has been usedto find the significance of study parameters between the studygroups.Results: The study showed that refractive status/axial lengthaffected the peripapillary RNFL thickness significantly.Conclusion: The study suggests that the diagnostic accuracy ofOCT may be improved by considering refractive status and axiallength of the eye when RNFL is measured.