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Mitral valve replacement in mitral stenosis; the problem of small left ventricle

机译:二尖瓣瓣膜置换二尖瓣狭窄;小左心室的问题

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摘要

Abstract Background Mitral valve stenosis in adults especially due to rheumatic heart disease may be associated with a smaller than normal left ventricular cavity. Mitral valve replacement in such cases may lead to hemodynamic instability either during weaning from cardiopulmonary bypass or in the early postoperative period manifested by the need for inotropic support and even mortality due to low cardiac output syndrome. Patients and methods 184 patients with predominately severe stenotic mitral valves who underwent elective isolated mitral valve replacement in the period between January 2012 and January 2018 at our hospital were included in this study. Patients were divided into 2 matched groups; (small LV group) consisting of 86 cases and (normal or dilated LV group) consisting of 98 cases. Results There were no statistically significant differences in operative details among both groups apart from the need for inotropic support and intra-aortic balloon pump due to low cardiac output which were statistically significantly higher in (small LV group) than (normal or dilated LV group) with a p-values of 0.01 and 0.03 respectively. Within the ICU stay only the incidence of occurrence of heart failure was significantly higher in (small LV group) with a p-value of 0.008. No statistically significant difference could be elicited in the in-hospital mortality between both groups (p-value = 0.1). Conclusion Patients with mitral valve stenosis and small left ventricular cavity are in a higher need for inotropic and even mechanical support after mitral valve replacement as well as at a higher risk for the development of heart failure before hospital discharge than patients with mitral stenosis and normal-sized left ventricular cavity.
机译:摘要背景,尤其是由于风湿性心脏病,二尖瓣瓣膜狭窄可能与小于正常左心室腔的腔有关。在这种情况下,二尖瓣瓣膜置换术后可能导致血液动力学不稳定,也可能导致从心肺旁路或在术后早期的术后期间由于低心输出综合征而甚至是死亡率的。患者和方法184例主要严重的狭窄二尖瓣患者在2012年1月至2018年1月期间接受选修孤立二尖瓣置换的患者纳入本研究。患者分为2个匹配组; (小型LV组)由86例和(正常或扩张的LV组)组成,包括98例。结果除了由于低心输出引起的官能载体和主动脉内球囊泵的需求外,两组的手术细节差异没有统计学显着的差异,这是统计学上(小LV组)的统计学显着高于(正常或扩张的LV组) P值分别为0.01和0.03。在ICU内,只有0.008的p值,(小型LV组)只有0.008的发生效果的发生率显着高。在两组之间的住院性死亡率中没有引发统计学上显着差异(p值= 0.1)。结论二尖瓣狭窄和小左心室腔的患者在二尖瓣置换术后均衡甚至机械载体的需求较高,以及在医院排放前的心力衰竭开发的风险高于二尖瓣狭窄和正常的患者大小的左心室腔。

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