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Clonal expansion and activation of tissue-resident memory-like TH17 cells expressing GM-CSF in the lungs of patients with severe COVID-19

机译：克隆扩张和激活组织常规记忆样Th17细胞在严重Covid-19肺部肺部表达GM-CSF的细胞

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Yu Zhao; Christoph Kilian; Jan-Eric Turner; Lidia Bosurgi; Kevin Roedl; Patricia Bartsch; Ann-Christin Gnirck; Filippo Cortesi; Christoph Schultheiß; Malte Hellmig; Leon U.B. Enk; Fabian Hausmann; Alina Borchers; Milagros N. Wong; Hans-Joachim Paust; Francesco Siracusa; Nicola Scheibel; Marissa Herrmann; Elisa Rosati; Petra Bacher; Dominik Kylies; Dominik Jarczak; Marc Lütgehetmann; Susanne Pfefferle; Stefan Steurer; Julian Schulze zur Wiesch; Victor G. Puelles; Jan-Peter Sperhake; Marylyn M. Addo; Ansgar W. Lohse; Mascha Binder; Samuel Huber; Tobias B. Huber; Stefan Kluge; Stefan Bonn; Ulf Panzer; Nicola Gagliani; Christian F. Krebs;
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1. Severe dry eye disease in aged mice is associated with an expanded memory Th17 cell response and higher frequencies of IFN-gamma-expressing Th17 Cells [J] . Foulsham William, Chen Yihe, Nakao Takeshi, Investigative ophthalmology & visual science . 2018,第9期

机译：老年小鼠的严重干眼症与膨胀的记忆TH17细胞响应和IFN-Gamma-Th17细胞的较高频率有关
2. Severe dry eye disease in aged mice is associated with an expanded memory Th17 cell response and higher frequencies of IFN-gamma-expressing Th17 Cells [J] . Foulsham William, Chen Yihe, Nakao Takeshi, Investigative ophthalmology & visual science . 2018,第9期

机译：老年小鼠的严重干眼症与膨胀的记忆TH17细胞响应和IFN-Gamma-Th17细胞的较高频率有关
3. GM-CSF plays a key role in zymosan-stimulated human dendritic cells for activation of Th1 and Th17 cells. [J] . Wei WC, Su YH, Chen SS, Cytokine . 2011,第1期

机译：GM-CSF在经酵母聚糖刺激的人树突状细胞中激活Th1和Th17细胞起着关键作用。
4. THE INHIBITORY Fcy-RECEPTOR MB (CD32B) IS HIGHLY EXPRESSED ON CLONAL PLASMA CELLS FROM PATIENTS WITH SYSTEMIC LIGHT-CHAIN (AL) AMYLOIDOSIS AND PROVIDES A TARGET FOR MONOCLONAL ANTIBODY THERAPY [C] . P. Zhou, A B Olshen, E Bonvini, International Symposium on Amyloidosis . 2008

机译：抑制性FCY-受体MB（CD32B）对来自全身轻链（AL）淀粉样蛋白症患者的克隆血浆细胞高度表达，并为单克隆抗体治疗提供靶标
5. Gene expression analysis of human non -small cell lung cancer subtypes, adenocarcinoma and squamous cell carcinoma, and mouse lung epithelial cell lines: Implications in lung tumorigenesis [D] . Silvers, Amy Lynn. 2002

机译：人类非小细胞肺癌亚型，腺癌和鳞状细胞癌以及小鼠肺上皮细胞系的基因表达分析：在肺肿瘤发生中的意义
6. T Cell Activation Highly Armed Cytotoxic Cells and a Shift in Monocytes CD300 Receptors Expression Is Characteristic of Patients With Severe COVID-19 [O] . Olatz Zenarruzabeitia, Gabirel Astarloa-Pando, Iñigo Terrén, 2021

机译：T细胞活化高臂细胞毒性细胞和单核细胞CD300受体表达的转变是严重Covid-19患者的特征
7. Reduced Expression of Autophagy Markers and Expansion of Myeloid-Derived Suppressor Cells Correlate With Poor T Cell Response in Severe COVID-19 Patients [O] . Sergej Tomić, Jelena Đokić, Dejan Stevanović, 2021

机译：减少自噬标志物的表达和粘骨衍生的抑制细胞的扩张与严重Covid-19患者中的差T细胞反应相关

Clonal expansion and activation of tissue-resident memory-like TH17 cells expressing GM-CSF in the lungs of patients with severe COVID-19

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