首页> 外文OA文献 >DUETTE: a phase II randomized, multicenter study to investigate the efficacy and tolerability of a second maintenance treatment in patients with platinum-sensitive relapsed epithelial ovarian cancer, who have previously received poly(ADP-ribose) polymerase (PARP) inhibitor maintenance treatment

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DUETTE: a phase II randomized, multicenter study to investigate the efficacy and tolerability of a second maintenance treatment in patients with platinum-sensitive relapsed epithelial ovarian cancer, who have previously received poly(ADP-ribose) polymerase (PARP) inhibitor maintenance treatment

机译：Duette：II期随机的多中心研究，以研究预先接受聚（ADP-核糖）聚合酶（PARP）抑制剂维持治疗的铂 - 敏感复发的上皮卵巢癌患者的第二次维持治疗的功效和耐受性

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Michelle McMullen; Katherine Karakasis; Bienvenu Loembe; Emma Dean; Graem Parr; Amit M Oza;
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1. Phase II, open-label, randomized, multicenter study comparing the efficacy and safety of olaparib, a poly (ADP-ribose) polymerase inhibitor, and pegylated liposomal doxorubicin in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer [J] . KayeS.B., LubinskiJ., MatulonisU., Journal of Clinical Oncology . 2012,第4期

机译：II期开放标签，随机，多中心研究，比较多聚（ADP-核糖）聚合酶抑制剂奥拉帕尼和聚乙二醇化脂质体阿霉素对患有BRCA1或BRCA2突变和复发性卵巢癌的患者的疗效和安全性
2. PARP (Poly(ADP-Ribose) Polymerase) Inhibitors in Platinum-Sensitive Recurrent Ovarian Cancer: A Meta-Analysis of Randomized Controlled Trials [J] . Al Hadidi Samer, Aburahma Ahmed, Badami Sunil, Oncology research and treatment. . 2018,第4期

机译：PARP（聚（ADP-核糖）聚合酶）铂敏感复发性卵巢癌中的抑制剂：随机对照试验的荟萃分析
3. G2 Efficacy of BSI-201, a poly (ADP-ribose) polymerase-1 (PARP1) inhibitor, in combination with gemcitabine/carboplatin (G/C) in patients with metastatic triple-negative breast cancer (TNBC): results of a randomized phase II trial [J] . J.OShaughnessy, C.Osborne, J.Pippen, European Journal of Cancer Supplements . 2009,第3期

机译：聚（ADP-核糖）聚合酶-1（PARP1）抑制剂BSI-201与吉西他滨/卡铂（G / C）联用在转移性三阴性乳腺癌（TNBC）患者中的G2疗效：随机结果II期试验
4. DESIGN AND SYNTHESIS OF NOVEL POLY ADP-RIBOSE POLYMERASE 1(PARP1)INHIBITORS FOR THE TREATMENT OF SOLID TUMORS [C] . J.Priyancy, D.P.Bhumika Conference on Drug Design and Discovery Technologies . 2020

机译：用于治疗实体肿瘤的新型聚ADP-核糖聚合酶1（PARP1）抑制剂的设计与合成
5. Molecular determinants of sensitivity to poly(ADP-ribose) polymerase inhibitors in epithelial ovarian cancer. [D] . O'Connor, Kevin. 2016

机译：分子决定因素对上皮性卵巢癌中聚（ADP-核糖）聚合酶抑制剂的敏感性。
6. Comparison of Poly (ADP-ribose) Polymerase Inhibitors (PARPis) as Maintenance Therapy for Platinum-Sensitive Ovarian Cancer: Systematic Review and Network Meta-Analysis [O] . Amos Stemmer, Inbal Shafran, Salomon M. Stemmer, 2020

机译：聚（ADP-核糖）聚合酶抑制剂（PARPI）对铂敏感卵巢癌的维持治疗的比较：系统审查与网络元分析
7. Efficacy and safety updates of poly ADP-ribose polymerase (PARP) inhibitor maintenance in ovarian cancer from ASCO 2020 [O] . Ainhoa Madariaga, Luisa Bonilla, Michelle McMullen, 2020

机译：来自ASCO 2020的卵巢癌中聚ADP-核糖聚合酶（PARP）抑制剂维持的功效和安全更新
8. Treatment of BRCA1/2 Hereditary Breast Cancer and Sporadic Breast Cancer with Poly(ADP-ribose) PARP-1 Inhibitors and Chemotherapy [R] . DeSoto, J. A. 2008

机译：聚（aDp-核糖）paRp-1抑制剂和化疗治疗BRCa1 / 2遗传性乳腺癌和散发性乳腺癌

DUETTE: a phase II randomized, multicenter study to investigate the efficacy and tolerability of a second maintenance treatment in patients with platinum-sensitive relapsed epithelial ovarian cancer, who have previously received poly(ADP-ribose) polymerase (PARP) inhibitor maintenance treatment

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