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Mutagenesis of CXCR4 Identifies Important Domains for Human Immunodeficiency Virus Type 1 X4 Isolate Envelope-Mediated Membrane Fusion and Virus Entry and Reveals Cryptic Coreceptor Activity for R5 Isolates

机译：CXCR4的诱变鉴定了人免疫缺陷病毒型1 X4分离型包膜介导的膜融合和病毒进入的重要结构域，并揭示了R5分离株的隐秘团体活性

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Donald J. Chabot; Peng-Fei Zhang; Gerald V. Quinnan; Christopher C. Broder;
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年度 1999
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1. R5 to X4 coreceptor switch of human immunodeficiency virus type 1 B' and B'/C recombinant subtype isolates in China [J] . GUO Yan-fang, ZHANG Xiao-yan, RUAN Yu-hua, 中华医学杂志（英文版） . 2007,第006期

机译：中国人类免疫缺陷病毒1型B'和B'/ C重组亚型分离株的R5至X4共受体开关
2. Interaction between virion-bound host intercellular adhesion molecule-1 and the high-affinity state of lymphocyte function-associated antigen-1 on target cells renders R5 and X4 isolates of human immunodeficiency virus type 1 more refractory to neutr [J] . Fortin JF, Cantin R, Bergeron MG, Virology . 2000,第2期

机译：病毒体结合的宿主细胞间粘附分子-1与靶细胞上与淋巴细胞功能相关的抗原-1的高亲和力状态之间的相互作用，使人免疫缺陷病毒1型的R5和X4分离株对中性更难治
3. Entry of R5X4 and X4 human immunodeficiency virus type 1 strains is mediated by negatively charged and tyrosine residues in the amino-terminal domain and the second extracellular loop of CXCR4. [J] . Kajumo F, Thompson DA, Guo Y, Virology . 2000,第2期

机译：R5X4和X4型人类免疫缺陷病毒1型毒株的进入是由CXCR4的氨基末端结构域和第二个细胞外环中的负电荷和酪氨酸残基介导的。
4. Variability in the Glycosylation Patterns of gp120 proteins From Different Human Immunodeficiency Virus Type 1 Isolates Expressed in Different Host Cells [C] . Ehwang Song, Samantha Rice, Fan Jiang, ASMS Conference on Mass Spectrometry and Allied Topics . 2014

机译：来自不同人免疫缺陷病毒的GP120蛋白的糖基化模式的可变性1型分离物在不同宿主细胞中表达
5. The role of the transmembrane and cytoplasmic domains of the VPU protein of human immunodeficiency virus type 1 (HIV-1) in the acute CD4+ T cell loss and disease in the simian human immunodeficiency virus (SHIV)/macaque model. [D] . Hout, David Richard. 2006

机译：人类免疫缺陷病毒1型（HIV-1）的VPU蛋白的跨膜和胞质域在猿猴人类免疫缺陷病毒（SHIV）/猕猴模型的急性CD4 + T细胞丧失和疾病中的作用。
6. Mutagenesis of CXCR4 Identifies Important Domains for Human Immunodeficiency Virus Type 1 X4 Isolate Envelope-Mediated Membrane Fusion and Virus Entry and Reveals Cryptic Coreceptor Activity for R5 Isolates [O] . Donald J. Chabot, Peng-Fei Zhang, Gerald V. Quinnan, 1999

机译：CXCR4的诱变确定了人类免疫缺陷病毒1型X4分离包膜介导的膜融合和病毒进入的重要域并揭示了R5分离株的隐秘受体活性。
7. Sequential CD4-Coreceptor Interactions in Human Immunodeficiency Virus Type 1 Env Function: Soluble CD4 Activates Env for Coreceptor-Dependent Fusion and Reveals Blocking Activities of Antibodies against Cryptic Conserved Epitopes on gp120 [O] . Salzwedel, Karl, Smith, Erica D., Dey, Barna, 2000

机译：在人类免疫缺陷病毒1型Env中的顺序CD4-Coreceptor相互作用：可溶性CD4激活Env进行Coreceptor依赖性融合，并揭示针对gp120上的隐秘保守表位的抗体的阻断活性。
8. Characterization and Enhanced Processing of Soluble, Oligomeric GP140 Envelope Glycoproteins Derived from Human Immunodeficiency Virus Type-1 Primary Isolates [R] . Jones-Trower, A. Y. 2001

机译：人类免疫缺陷病毒1型初级分离株衍生的可溶性寡聚Gp140包膜糖蛋白的表征和增强加工

Mutagenesis of CXCR4 Identifies Important Domains for Human Immunodeficiency Virus Type 1 X4 Isolate Envelope-Mediated Membrane Fusion and Virus Entry and Reveals Cryptic Coreceptor Activity for R5 Isolates

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