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Dosage reduction and discontinuation of biological disease-modifying antirheumatic drugs in patients with rheumatoid arthritis, psoriatic arthritis and axial spondyloarthritis: protocol for a pragmatic, randomised controlled trial (the BIOlogical Dose OPTimisation (BIODOPT) trial)

机译：类风湿性关节炎患者，银屑病关节炎和轴向脊椎炎患者的生物疾病改性药物的剂量减少和停止，用于务实，随机对照试验的典礼（生物剂量优化（BIODOPT）试验）

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Line Uhrenholt; Annette Schlemmer; Ellen-Margrethe Hauge; Robin Christensen; Lene Dreyer; Maria E Suarez-Almazor; Salome Kristensen;
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1. First-time prescriptions of biological disease-modifying antirheumatic drugs in rheumatoid arthritis, psoriatic arthritis and axial spondyloarthritis 2002-2011: data from the NOR-DMARD register [J] . Elisabeth Lie, Karen M Fagerli, Knut Mikkelsen, Annals of the Rheumatic Diseases: A Journal of Clinical Rheumatology and Connective Tissue Research . 2014,第10期

机译：2002-2011年在类风湿性关节炎，银屑病性关节炎和轴向性脊椎关节炎中首次使用可改变生物疾病的抗风湿药处方：NOR-DMARD注册数据
2. Dose reduction and withdrawal strategy for TNF-inhibitors in psoriatic arthritis and axial spondyloarthritis: design of a pragmatic open-label, randomised, non-inferiority trial [J] . Celia A. J. Michielsens, Nadine Boers, Nathan den Broeder, Trials . 2020,第1期

机译：银屑病关节炎和轴向脊椎关节炎TNF抑制剂的剂量减少和戒断策略：务实开放标签，随机性，非劣级试验的设计
3. An overview of biologic disease-modifying antirheumatic drugs in axial spondyloarthritis and psoriatic arthritis [J] . Anthony So, Robert Davies Inman Best practice & research:Clinical rheumatology . 2018,第3期

机译：轴向脊椎关节炎和银屑病关节炎中生物疾病改性抗逆肿瘤的概述
4. Dosage reduction and discontinuation of biological disease-modifying antirheumatic drugs in patients with rheumatoid arthritis psoriatic arthritis and axial spondyloarthritis: protocol for a pragmatic randomised controlled trial (the BIOlogical Dose OPTimisation (BIODOPT) trial) [O] . Line Uhrenholt, Annette Schlemmer, Ellen-Margrethe Hauge, 2019

机译：类风湿性关节炎银屑病性关节炎和轴向性脊柱关节炎患者减少剂量和中止改变生物疾病的抗风湿药：一项实用随机对照试验的方案（生物剂量优化（BIODOPT）试验）
5. Ultrasound-detected bone erosion is a relapse risk factor after discontinuation of biologic disease-modifying antirheumatic drugs in patients with rheumatoid arthritis whose ultrasound power Doppler synovitis activity and clinical disease activity are well controlled [O] . Kawashiri Shin-ya, Fujikawa Keita, Nishino Ayako, 2017

机译：超声检测的骨侵蚀是类风湿性关节炎患者停用改良生物疾病的抗风湿药后复发的危险因素，其超声功率多普勒滑膜炎活动和临床疾病活动得到很好的控制

Dosage reduction and discontinuation of biological disease-modifying antirheumatic drugs in patients with rheumatoid arthritis, psoriatic arthritis and axial spondyloarthritis: protocol for a pragmatic, randomised controlled trial (the BIOlogical Dose OPTimisation (BIODOPT) trial)

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