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Development of pyridyl thiosemicarbazones as highly potent agents for the treatment of malaria after oral administration

机译：吡啶基硫代蓟虫萎缩作为口服给药后疟疾治疗疟疾的高效药物

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Christopher J Parkinson; Geoffrey W Birrell; Marina Chavchich; Donna Mackenzie; Richard K Haynes; Carmen de Kock; Des R Richardson; Michael D Edstein;
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1. Development of pyridyl thiosemicarbazones as highly potent agents for the treatment of malaria after oral administration [J] . Parkinson Christopher J., Birrell Geoffrey W., Chavchich Marina, The Journal of Antimicrobial Chemotherapy . 2019,第10期

机译：吡啶基硫代蓟虫萎缩作为口服给药后疟疾治疗的高效药物
2. Development of potent oral nanoparticulate formulation of coenzyme Q10 for treatment of hypertension: can the simple nutritional supplements be used as first line therapeutic agents for prophylaxis/therapy? [J] . Ankola DD, Viswanad B, Bhardwaj V, European journal of pharmaceutics and biopharmaceutics: official journal of Arbeitsgemeinschaft fuer Pharmazeutische Verfahrenstechnik e.V . 2007,第2期

机译：开发用于治疗高血压的强效口服辅酶Q10纳米颗粒制剂：这种简单的营养补品可以用作预防/治疗的一线治疗剂吗？
3. Discovery of a potent, orally bioavailable and highly selective human neuronal nitric oxide synthase (nNOS) inhibitor, N-(1-(piperidin-4-yl)indolin-5- yl)thiophene-2-carboximidamide as a pre-clinical development candidate for the treatment of migraine [J] . AnnediS.C., MaddafordS.P., RamnauthJ., European Journal of Medicinal Chemistry: Chimie Therapeutique . 2012,第Null期

机译：发现一种有效的，口服生物利用度和高选择性的人类神经元一氧化氮合酶（nNOS）抑制剂N-（1-（1-哌啶丁-4-基）吲哚满-5-基）噻吩-2-羧酰亚胺作为临床前开发候选药物用于治疗偏头痛
4. Development of Cationic Shell-crosslinked Knedel-like Nanoparticles as Highly Potent Transfection Agents [C] . Ke Zhang, Huafeng Fang, Gang Shen PMSE Symposia . 2009

机译：开发阳离子壳交联的Knedel样纳米粒子作为高效转染剂
5. Development of Orally Bioavailable 4(1H)-Quinolones and 1,2,3,4-Tetrahydroacridin-9(10H)-ones with Potent Anti-malarial Activity [D] . Maignan, Jordany R. 2015

机译：具有有效抗疟疾活性的口服生物可利用的4（1H）-喹诺酮和1,2,3,4-Tetrahydroacridin-9（10H）-ones的开发
6. Novel and potent anti-tumor and anti-metastatic di-2-pyridylketone thiosemicarbazones demonstrate marked differences in pharmacology between the first and second generation lead agents [O] . Vit Sestak, Jan Stariat, Jolana Cermanova, 2015

机译：新型有效的抗肿瘤和抗转移性二-2-吡啶基酮硫代半氨基甲酮在第一代和第二代前导药物之间显示出药理学上的显着差异
7. Highly Potent and Orally Active CCR5 Antagonists as Anti-HIV-1 Agents: Synthesis and Biological Activities of 1-Benzazocine Derivatives Containing a Sulfoxide Moiety [O] . -1

机译：高效且口服活性CCR5拮抗剂作为抗HIV-1剂：1-苯并杂志衍生物的合成和生物活性含有亚砜部分
8. Development of Potent Orally Active Agents for Prevention and Treatment of Poxvirus Infection. [R] . Hostetler, K. Y. 2003

机译：开发强效口服活性剂预防和治疗痘病毒感染。

Development of pyridyl thiosemicarbazones as highly potent agents for the treatment of malaria after oral administration

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