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Significantly Improved Pharmacokinetics Enhances In Vivo Efficacy of APX001 against Echinocandin- and Multidrug-Resistant Candida Isolates in a Mouse Model of Invasive Candidiasis

机译：显着改善的药代动力学在侵入性念珠菌病的小鼠模型中，在APX001对APX001的体内疗效增强了APX001的体内疗效

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Yanan Zhao; Min Hee Lee; Padmaja Paderu; Annie Lee; Cristina Jimenez-Ortigosa; Steven Park; Robert S. Mansbach; Karen Joy Shaw; David S. Perlin;
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1. Significantly Improved Pharmacokinetics Enhances In Vivo Efficacy of APX001 against Echinocandin- and Multidrug-Resistant Candida Isolates in a Mouse Model of Invasive Candidiasis [J] . Zhao Yanan, Lee Min Hee, Paderu Padmaja, Antimicrobial agents and chemotherapy. . 2018,第10期

机译：显着改善的药代动力学在侵入性念珠菌病的小鼠模型中，APX001对APX001的体内疗效增强了APX001的体内疗效
2. In Vivo Pharmacokinetics and Pharmacodynamics of APX001 against Candida spp. in a Neutropenic Disseminated Candidiasis Mouse Model [J] . Zhao Miao, Lepak Alexander J., VanScoy Brian, Antimicrobial agents and chemotherapy. . 2018,第4期

机译：在APX001的体内药代动力学和念珠菌SPP中的药效学。在中性介质播散的念珠菌病毒鼠标模型中
3. Efficacy of Delayed Therapy with Fosmanogepix (APX001) in a Murine Model of Candida auris Invasive Candidiasis [J] . Wiederhold Nathan P., Najvar Laura K., Shaw Karen J., Antimicrobial agents and chemotherapy. . 2019,第11期

机译：延迟治疗与FOSMANOGEPIX（APX001）在念珠菌的念珠菌蛋白模型中的疗效
4. HPMA HYDROGEL-BASED DRUG DELIVERY SYSTEM: PHARMACOKINETIC AND IN VIVO EFFICACY IN SENSITIVE AND MULTIDRUG RESISTANT CANCER MODELS [C] . M. Stastny, D. Plocova, K. Ulbrich, International symposium on controlled release of bioactive materials;Consumer diversified products conference . 2001

机译：基于HPMA水凝胶的药物输送系统：敏感和多药耐药癌症模型中的药动学和体内药效
5. Investigations of the biodistribution and phototherapeutic utility of two palladium(II)-containing macrocyclic drugs in a tumour-bearing mouse model: A study of the pharmacokinetics and tissue distribution of the potential photodynamic drug palladium-bacteriopheophorbide as well as the in vivo treatment efficacy and tissue distribution of the potential photothermal drug palladium(II) octabutoxynaphthalocyanine. [D] . DeGroot, Jennifer Leanne. 2002

机译：两种含钯（II）的大环药物在荷瘤小鼠模型中的生物分布和光疗实用性的研究：潜在的光动力药物钯-细菌脱镁叶绿酸的药代动力学和组织分布以及体内治疗效果和研究光热药物钯（II）八丁氧基萘酞菁的组织分布。
6. Significantly Improved Pharmacokinetics Enhances In Vivo Efficacy of APX001 against Echinocandin- and Multidrug-Resistant Candida Isolates in a Mouse Model of Invasive Candidiasis [O] . Yanan Zhao, Min Hee Lee, Padmaja Paderu, 2018

机译：在侵袭性念珠菌病小鼠模型中显着改善的药代动力学增强了APX001对棘手and和多药耐药念珠菌分离株的体内功效。
7. In Vivo Pharmacokinetics and Pharmacodynamics of APX001 against Candida spp. in a Neutropenic Disseminated Candidiasis Mouse Model [O] . Miao Zhao, Alexander J. Lepak, Brian VanScoy, 2018

机译：在APX001的体内药代动力学和对念珠菌SPP的药效动力学。在中性化播散的念珠菌病小鼠模型中

Significantly Improved Pharmacokinetics Enhances In Vivo Efficacy of APX001 against Echinocandin- and Multidrug-Resistant Candida Isolates in a Mouse Model of Invasive Candidiasis

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