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Preclinical Pharmacokinetic/Pharmacodynamic Studies and Clinical Trials in the Drug Development Process of EMA-Approved Antibacterial Agents: A Review

机译：EMA批准的抗菌剂药物开发过程中临床前药代动力学/药效学研究和临床试验：综述

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Anselm Jorda; Markus Zeitlinger;
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1. Considerations for Dose Selection and Clinical Pharmacokinetics/Pharmacodynamics for the Development of Antibacterial Agents [J] . Rizk M. L., Bhavnani S. M., Drusano G., Antimicrobial agents and chemotherapy. . 2019,第5期

机译：用于剂量选择和临床药代动力学/药效学的抗菌剂的考虑因素
2. Antibody-Drug Conjugates: Pharmacokinetic/Pharmacodynamic Modeling, Preclinical Characterization, Clinical Studies, and Lessons Learned [J] . Hedrich William D., Fandy Tamer E., Ashour Hossam M., Clinical pharmacokinetics . 2018,第6期

机译：抗体 - 药物缀合物：药代动力学/药效学建模，临床前表征，临床研究和学习的经验教训
3. Effects of hypothermia on pharmacokinetics and pharmacodynamics: a systematic review of preclinical and clinical studies. [J] . van den Broek MP, Groenendaal F, Egberts AC, Clinical pharmacokinetics . 2010,第5期

机译：亚低温对药代动力学和药效学的影响：临床前和临床研究的系统综述。
4. PHARMACOKINETIC AND PHARMACODYNAMIC MODELS FOR THE STUDY OF DRUGS OF ABUSE AND THERAPEUTIC MEDICATIONS IN THE EQUINE RACING INDUSTRY [C] . . 2005

机译：马术竞赛中药物滥用和治疗药物的药代动力学和药代动力学模型
5. Preclinical pharmacokinetic and tolerance assessment and phase I clinical trial of MU-Gold, a novel chemotherapeutic agent. [D] . Higginbotham, Mary Lynn. 2004

机译：新型化学治疗剂MU-Gold的临床前药代动力学和耐受性评估以及I期临床试验。
6. Considerations for Dose Selection and Clinical Pharmacokinetics/Pharmacodynamics for the Development of Antibacterial Agents [O] . M. L. Rizk, S. M. Bhavnani, G. Drusano, 2019

机译：抗菌药物开发的剂量选择和临床药代动力学/药效学注意事项
7. Pharmacokinetics/Pharmacodynamics of Antiviral Agents Used to Treat SARS-CoV-2 and Their Potential Interaction with Drugs and Other Supportive Measures: A Comprehensive Review by the PK/PD of Anti-Infectives Study Group of the European Society of Antimicrobial Agents [O] . Markus Zeitlinger, Birgit C. P. Koch, Roger Bruggemann, 2020

机译：用于治疗SARS-COV-2的抗病毒剂的药代动力学/药效学及其与药物的潜在互动以及其他支持措施：抗病性研究小组PK / PD综合审查欧洲抗菌药物学会

Preclinical Pharmacokinetic/Pharmacodynamic Studies and Clinical Trials in the Drug Development Process of EMA-Approved Antibacterial Agents: A Review

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