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A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells

机译：一种新的LSD1抑制剂T-3775440破坏了含GFI1B的综合体，导致转染细胞和AML细胞的生长受损

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Yoshinori Ishikawa; Kanae Gamo; Masato Yabuki; Shinji Takagi; Kosei Toyoshima; Kazuhide Nakayama; Akiko Nakayama; Megumi Morimoto; Hitoshi Miyashita; Ryo Dairiki; Yukiko Hikichi; Naoki Tomita; Daisuke Tomita; Shinichi Imamura; Misa Iwatani; Yusuke Kamada; Satoru Matsumoto; Ryujiro Hara; Toshiyuki Nomura; Ken Tsuchida; Kazuhide Nakamura;
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1. Correction: Synergistic anti-AML effects of the LSD1 inhibitor T-3775440 and the NEDD8-activating enzyme inhibitor pevonedistat via transdifferentiation and DNA rereplication [J] . Y. Ishikawa, K. Nakayama, M. Morimoto, Oncogenesis. . 2019,第9期

机译：校正：LSD1抑制剂T-3775440的协同抗AML效应，通过转染和DNA重生，NEDD8活化酶抑制剂PEVONEDISTAT
2. Synergistic anti-AML effects of the LSD1 inhibitor T-3775440 and the NEDD8-activating enzyme inhibitor pevonedistat via transdifferentiation and DNA rereplication [J] . Y Ishikawa, K Nakayama, M Morimoto, Oncogenesis. . 2017,第9期

机译：LSD1抑制剂T-3775440和NEDD8激活酶抑制剂Pevonedistat的协同抗AML效应通过转染和DNA重生
3. LSD1 Inhibitor T-3775440 Inhibits SCLC Cell Proliferation by Disrupting LSD1 Interactions with SNAG Domain Proteins INSM1 and GFI1B [J] . Takagi Shinji, Ishikawa Yoshinori, Mizutani Akio, Cancer research: The official organ of the American Association for Cancer Research, Inc . 2017,第17期

机译：LSD1抑制剂T-3775440通过破坏与SNAG结构域蛋白质INSM1和GFI1b的LSD1相互作用来抑制SCLC细胞增殖
4. A complex network of intra- and intercellular mediators regulate cellular activation and transdifferentiation of hepatic stellate cells [C] . R. WEISKIRCHEN, E. BORKHAM-KAMPHORST, S. K. MEURER, Falk Symposium . 2008

机译：内细胞间介质的复杂网络调节肝星状细胞的细胞活化和转染细胞
5. Targeting Protein-Protein Interactions for Disruption of LSD1 (KDM1A) Complexes [D] . Schwabe, Jennifer Link. 2017

机译：靶向蛋白质-蛋白质相互作用破坏LSD1（KDM1A）复合物
6. Correction: Synergistic anti-AML effects of the LSD1 inhibitor T-3775440 and the NEDD8-activating enzyme inhibitor pevonedistat via transdifferentiation and DNA rereplication [O] . Y. Ishikawa, K. Nakayama, M. Morimoto, 2019

机译：更正：LSD1抑制剂T-3775440和NEDD8激活酶抑制剂pevonedistat通过转分化和DNA复制的协同抗AML效应
7. Correction: Synergistic anti-AML effects of the LSD1 inhibitor T-3775440 and the NEDD8-activating enzyme inhibitor pevonedistat via transdifferentiation and DNA rereplication [O] . Y. Ishikawa, K. Nakayama, M. Morimoto, 2019

机译：校正：LSD1抑制剂T-3775440的协同抗AML效应，通过转染和DNA重生，NEDD8活化酶抑制剂PEVONEDISTAT

A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells

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