首页> 外文OA文献 >The Bruton Tyrosine Kinase (BTK) Inhibitor Acalabrutinib Demonstrates Potent On-Target Effects and Efficacy in Two Mouse Models of Chronic Lymphocytic Leukemia

【2h】

The Bruton Tyrosine Kinase (BTK) Inhibitor Acalabrutinib Demonstrates Potent On-Target Effects and Efficacy in Two Mouse Models of Chronic Lymphocytic Leukemia

机译：Bruton Tyrosine激酶（BTK）抑制剂Acalabrutinib在两种小鼠慢性淋巴细胞白血病模型中显示出有效的靶向效果和功效

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

著录项
引文网络
相似文献
相关主题

著录项

作者
Sarah E.M. Herman; Arnau Montraveta; Carsten U. Niemann; Helena Mora-Jensen; Michael Gulrajani; Fanny Krantz; Rose Mantel; Lisa L. Smith; Fabienne McClanahan; Bonnie K. Harrington; Dolors Colomer; Todd Covey; John C. Byrd; Raquel Izumi; Allard Kaptein; Roger Ulrich; Amy J. Johnson; Brian J. Lannutti; Adrian Wiestner; Jennifer A. Woyach;
展开▼
作者单位

展开▼
年度 2016
总页数
原文格式 PDF
正文语种
中图分类

相似文献

外文文献
中文文献
专利

1. Variable Bruton Tyrosine Kinase (BTK) Resynthesis across Patients with Chronic Lymphocytic Leukemia (CLL) on Acalabrutinib Therapy Affect Target Occupancy and Reactivation of B-Cell Receptor (BCR) Signaling [J] . Alsadhan Anfal A., Cheung Jean, Gulrajani Michael, Blood: The Journal of the American Society of Hematology . 2018,第NovaelaTreatmentAppr期

机译：对慢性淋巴细胞白血病（CLL）患者的可变Bruton酪氨酸激酶（BTK）对Acalabrutinib治疗的患者进行影响，影响B细胞受体（BCR）信号传导的目标占用和再活化
2. 32. Chronic lymphocytic leukemia patients who develop resistance to Bruton Tyrosine Kinase (BTK) inhibitors demonstrate heterogeneous patterns of clonal evolution [J] . Rashmi Kanagal-Shamanna, Preetesh Jain, Keyur Patel, Cancer genetics . 2018,第期

机译：32.慢性淋巴细胞白血病患者，对镇静酪氨酸激酶（BTK）抑制剂产生抗性的患者表现出克隆演化的异质模式
3. Bruton’s tyrosine kinase mediated signaling enhances leukemogenesis in a mouse model for chronic lymphocytic leukemia [J] . Laurens P Kil, Marjolein JW de Bruijn, Jennifer AC van Hulst, American Journal of Blood Research . 2013,第1期

机译：布鲁顿酪氨酸激酶介导的信号增强慢性淋巴细胞性白血病小鼠模型的白血病发生
4. Combination effects of repetitive pulsed magnetic stimulation and tyrosine kinase inhibitor imatinib for chronic myeloid leukemia cell line TCC-S [C] . S. Yamaguchi, M. Sekino, Y. Sato, Intermag Conference . 2006

机译：重复脉冲磁刺激和酪氨酸激酶抑制剂慢性髓性白血病细胞系TCC-S的组合效应
5. An RNAi screen targeting the protein tyrosine kinases identifies Bruton's tyrosine kinase (BTK) as a breast cancer cell survival factor. [D] . Eifert, Cheryl. 2009

机译：靶向蛋白质酪氨酸激酶的RNAi筛选可将布鲁顿酪氨酸激酶（BTK）识别为乳腺癌细胞生存因子。
6. The Bruton’s tyrosine kinase (BTK) inhibitor acalabrutinib demonstrates potent on-target effects and efficacy in two mouse models of chronic lymphocytic leukemia [O] . Sarah E. M. Herman, Arnau Montraveta, Carsten U. Niemann, -1

机译：Bruton的酪氨酸激酶（BTK）抑制剂aacalabrutinib在两种慢性淋巴细胞性白血病小鼠模型中均显示出强大的靶向作用和功效
7. SAT0056 TAS5315, A NOVEL BRUTON’S TYROSINE KINASE INHIBITOR, DEMONSTRATES POTENT EFFICACY AGAINST BONE DESTRUCTION IN AN ANIMAL MODEL FOR RHEUMATOID ARTHRITIS [O] . Naruto Noma, Fumihito Hosoi, Satoru Iguchi, 2019

机译：新颖的Bruton的酪氨酸激酶抑制剂SAT0056 TAS5315证明了对类风湿性关节炎动物模型中的骨破坏有效的功效

The Bruton Tyrosine Kinase (BTK) Inhibitor Acalabrutinib Demonstrates Potent On-Target Effects and Efficacy in Two Mouse Models of Chronic Lymphocytic Leukemia

著录项

引文网络

相似文献

相关主题

期刊订阅