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MDM2 inhibitor APG-115 exerts potent antitumor activity and synergizes with standard-of-care agents in preclinical acute myeloid leukemia models

机译：MDM2抑制剂APG-115施加有效的抗肿瘤活性，并用临床前急性髓性白血病模型中的护理标准剂进行促进

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Douglas D. Fang; Qiuqiong Tang; Yanhui Kong; Tao Rong; Qixin Wang; Na Li; Xu Fang; Jiaxing Gu; Dengkun Xiong; Yan Yin; Jing Deng; Dajun Yang; Yifan Zhai;
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1. MDM2 inhibitor APG-115 exerts potent antitumor activity and synergizes with standard-of-care agents in preclinical acute myeloid leukemia models [J] . Fang Douglas D., Tang Qiuqiong, Kong Yanhui, Cell death discovery. . 2021,第1期

机译：MDM2抑制剂APG-115施加有效的抗肿瘤活性，并用临床前急性髓性白血病模型中的护理标准剂协同
2. The CDK9 Inhibitor Dinaciclib Exerts Potent Apoptotic and Antitumor Effects in Preclinical Models of MLL-Rearranged Acute Myeloid Leukemia [J] . Baker Adele, Gregory Gareth P., Verbrugge Inge, Cancer research: The official organ of the American Association for Cancer Research, Inc . 2016,第5期

机译：CDK9抑制剂Dinaciclib在MLL重排的急性髓样白血病的临床前模型中具有强凋亡和抗肿瘤作用。
3. Inhibition of FLT3 and PIM Kinases by EC-70124 Exerts Potent Activity in Preclinical Models of Acute Myeloid Leukemia [J] . Noelia Puente-Moncada, Paula Costales, Isaac Antolín, Molecular cancer therapeutics . 2018,第3期

机译：EC-70124对FLT3和PIM激酶的抑制在急性髓性白血病的临床前模型中施加有效活性
4. Azanudeoside DNA Methyltransferase Inhibitor Drugs: Update on Clinical Applications in Myelodysplastic Syndromes and Acute Myeloid Leukemia [C] . Michael Lubbert, Michael Daskalakis, Philipp N. Ser, Weissenburg Symposium Biriciana . 2016

机译：硫代稳产苷DNA甲基转移酶抑制剂药物：更新骨髓增生综合征和急性髓性白血病的临床应用
5. Briciclib (on 013105), an elF4E inhibitor, exhibits potent anti-cancer activity in various preclinical cancer models. [D] . Desai, Bina. 2015

机译：elF4E抑制剂Briciclib（在013105上）在各种临床前癌症模型中均显示出强大的抗癌活性。
6. MDM2 inhibitor APG-115 exerts potent antitumor activity and synergizes with standard-of-care agents in preclinical acute myeloid leukemia models [O] . Douglas D. Fang, Qiuqiong Tang, Yanhui Kong, 2021

机译：MDM2抑制剂APG-115施加有效的抗肿瘤活性并用临床前急性髓性白血病模型中的护理标准剂进行促进
7. The CDK9 inhibitor dinaciclib exerts potent apoptotic and antitumor effects in preclinical models of MLL-rearranged acute myeloid Leukemia [O] . Baker, A, Gregory, GP, Verbrugge, I, 2016

机译：CDK9抑制剂dinaciclib在MLL重排的急性髓样白血病的临床前模型中发挥有效的凋亡和抗肿瘤作用

MDM2 inhibitor APG-115 exerts potent antitumor activity and synergizes with standard-of-care agents in preclinical acute myeloid leukemia models

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