首页> 外文OA文献 >Engineering domain-inlaid SaCas9 adenine base editors with reduced RNA off-targets and increased on-target DNA editing

【2h】

Engineering domain-inlaid SaCas9 adenine base editors with reduced RNA off-targets and increased on-target DNA editing

机译：工程域镶嵌Saca9腺嘌呤基础编辑器，具有降低的RNA脱靶并增加目标DNA编辑

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

著录项
引文网络
相似文献
相关主题

著录项

作者
Minh Thuan Nguyen Tran; Mohd Khairul Nizam Mohd Khalid; Qi Wang; Jacqueline K. R. Walker; Grace E. Lidgerwood; Kimberley L. Dilworth; Leszek Lisowski; Alice Pébay; Alex W. Hewitt;
展开▼
作者单位

展开▼
年度 2020
总页数
原文格式 PDF
正文语种
中图分类

相似文献

外文文献
中文文献
专利

1. Engineering domain-inlaid SaCas9 adenine base editors with reduced RNA off-targets and increased on-target DNA editing [J] . Minh Thuan Nguyen Tran, Mohd Khairul Nizam Mohd Khalid, Qi Wang, Nature Communications . 2020,第1期

机译：工程域镶嵌Saca9腺嘌呤基础编辑器，具有降低的RNA脱靶并增加目标DNA编辑
2. A rationally engineered cytosine base editor retains high on-target activity while reducing both DNA and RNA off-target effects [J] . Nature methods . 2020,第6期

机译：理性工程化的胞嘧啶碱基编辑器保留高目标活动，同时减少DNA和RNA脱靶效果
3. CRISPR DNA base editors with reduced RNA off-target and self-editing activities [J] . Grunewald Julian, Zhou Ronghao, Iyer Sowmya, Nature biotechnology . 2019,第9期

机译：CRISPR DNA基础编辑以降低RNA脱靶和自我编辑活动
4. Reduced base-base interactions between the DNA seed and RNA target are the major determinants of a significant reduction in the off-target effect due to DNA-seed-containing siRNA [C] . Ui-Tei K., Nishi K., Naito Y., Micro-NanoMechatronics and Human Science, 2009. MHS 2009 . 2009

机译：DNA种子与RNA靶之间的碱基间相互作用降低是由于含DNA种子的siRNA导致脱靶效应显着降低的主要决定因素
5. Improving Zinc Finger Nucleases -- Strategies for Increasing Gene Editing Activities and Evaluating Off-Target Effects. [D] . Ramirez, Cherie Lynn. 2012

机译：改善锌指核酸酶-增加基因编辑活性和评估脱靶效应的策略。
6. Analysis and minimization of cellular RNA editing by DNA adenine base editors [O] . Holly A. Rees, Christopher Wilson, Jordan L. Doman, 2019

机译：DNA腺嘌呤碱基编辑器对细胞RNA编辑的分析和最小化
7. CRISPR DNA base editors with reduced RNA off-target and self-editing activities [O] . Julian Grünewald, Ronghao Zhou, Sowmya Iyer, 2019

机译：CRISPR DNA基础编辑编辑降低RNA脱靶和自我编辑活动

Engineering domain-inlaid SaCas9 adenine base editors with reduced RNA off-targets and increased on-target DNA editing

著录项

引文网络

相似文献

相关主题

期刊订阅