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Studies of Bitter Peptides from Casein Hydrolyzate. III. Bitter Taste of Synthetic Analogs of BPIa (Arg–Gly–Pro–Pro–Phe–Ile–Val) Containing D-Proline or Glycine in Place of L-Proline

机译：酪蛋白水解产物的苦肽研究。 III。含有D-脯氨酸或甘氨酸的BPIA（Arg-Gly-Pro-Phe-val）的合成类似物的苦味代替L-脯氨酸

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Ichizo Miyake; Katsushige Kouge; Hidenori Kanehisa; Hideo Okai;
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年度 1983
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1. Synthesis of Tyr-Pro-Phe-Val-Glu-L-[3,4-~(3)H]Pro-Ile, Tyr-D-Ala-Phe-Gly-Tyr-L-[3,4-~(3)H]Pro-Ser-NH_(2), and Tyr-D-Ala-Phe-Gly-Tyr-D-[3,4-~(3)H]Pro-Ser-NH_(2), Labeled Analogs of Human β-Casomorphin and Dermorphin [J] . V. P. Shevchenko, I. Yu. Nagaev, L. Yu. Alfeeva, Radiochemistry . 2004,第1期

机译：Tyr-Pro-Phe-Val-Glu-L- [3,4-〜（3）H] Pro-Ile，Tyr-D-Ala-Phe-Gly-Tyr-L- [3,4-〜（ 3）H] Pro-Ser-NH_（2）和Tyr-D-Ala-Phe-Gly-Tyr-D- [3,4-〜（3）H] Pro-Ser-NH_（2），标记类似物β-Casomorphin和Dermorphin的合成
2. In vitro and in vivo pharmacological profile of PL-3994, a novel cyclic peptide (Hept-cyclo(Cys-His-Phe-d-Ala-Gly-Arg-d-Nle-Asp-Arg-Ile-Ser-Cys)-Tyr-[Arg mimetic]-NH2) natriuretic peptide receptor-A agonist that is resistant to neutral endopeptidase and acts as a bronchodilator [J] . EdelsonJ.D., MakhlinaM., SilvesterK.R., Pulmonary pharmacology & therapeutics . 2013,第2期

机译：新型环肽PL-3994的体外和体内药理学特征（庚环（Cys-His-Phe-d-Ala-Gly-Arg-Nle-Asp-Arg-Ile-Ser-Cys- Tyr- [Arg模拟] -NH2）利尿钠肽受体-A激动剂，对中性内肽酶具有抵抗力，并起支气管扩张剂的作用
3. Синтез Tyr-Pro-Phe-Val-Glu-L-[3,4-~3H]Pro-Ile, Tyr-D-Ala-Phe-Gly-Tyr-L-[3,4-~3H]Pro-Ser-NH_2 и Tyr-D-Ala-Phe-Gly-Tyr-D-[3,4-~3H]Pro-Ser-NH_2-меченых аналогов человеческого β-казоморфина и дерморф [J] . В. П. Шевченко, И. Ю. Нагаев, Л. Ю. Алфеева, Радиохимия . 2004,第1期

机译：Tyr-Pro-Phe-Val-Glu-L- [3,4-〜3H] Pro-Ile，Tyr-D-Ala-Phe-Gly-Tyr-L- [3,4-〜3H] Pro-Ser的合成-NH_2和Tyr-D-Ala-Phe-Gly-Tyr-D- [3,4-〜3H] Pro-Ser-NH_2标记的人β-酪蛋白和dermorph的类似物
4. Increasing supply of Met and Arg relative to Lys while maintaining ratios of Thr∶Phe,Lys∶Thr, Lys∶His, and Lys∶Val alters casein protein abundance via AA-induced upstream mammalian target of rapamycin signaling pathway and circadian clock of bovine mammary epithelial cells [C] . L.Y.Hu, Y.F.Chen, I.M.Cortes, The 6th International Symposium on Dairy Cow Nutrition and Milk Quality（第六届“奶牛营养与牛奶质量”国际研讨会）论文集 . -1

机译：越来越多的遇见和arg的供应，而相对于李斯，而且保持鼠窜，lys:tr，lys:his和lys:val通过AA诱导的雷帕霉素信号传导途径和牛乳清昼夜昼夜昼夜昼夜急性的哺乳动物，改变酪蛋白蛋白质丰富上皮细胞
5. In vitro and in vivo pharmacological profile of PL-3994 a novel cyclic peptide (Hept-cyclo(Cys-His-Phe-d-Ala-Gly-Arg-d-Nle-Asp-Arg-Ile-Ser-Cys)-Tyr-Arg mimetic-NH2) natriuretic peptide receptor-A agonist that is resistant to neutral endopeptidase and acts as a bronchodilator [O] . Jeffrey D. Edelson, Marie Makhlina, Kevin R. Silvester, -1

机译：体外和体内Pl-3994的体内药理学分布一种新型环状肽（Hept-Cyclo（Cys-His-Phe-Ala-Ala-Al-Al-Asp-Ass-Asp-Asc-Arg-arile-Ser-Ser-Ser-Cys） - Tyr-arg模拟物 -NH2）利钠肽受体 - 一种抗中性内肽酶的激动剂作为支气管扩张剂
6. Studies of Bitter Peptides from Casein Hydrolyzate. I. Synthesis of Bitter Peptide BPIa Corresponding to Arg–Gly–Pro–Pro–Phe–Ile–Val from Casein Hydrolyzate by Alkaline Proteinase ofBacillus subtilis [O] . Hiroshi Fukui, Hidenori Kanehisa, Norio Ishibashi, 1983

机译：酪蛋白水解产物的苦肽研究。 I.用枯草芽孢杆菌碱蛋白酶从酪蛋白水解产物的酪氨酸水解产物合成苦肽BPIA的合成

Studies of Bitter Peptides from Casein Hydrolyzate. III. Bitter Taste of Synthetic Analogs of BPIa (Arg–Gly–Pro–Pro–Phe–Ile–Val) Containing D-Proline or Glycine in Place of L-Proline

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