Figure 1: Example of visualization of long range contacts for: (A) regions, here enhancer-promoter contacts, for two 10 kb resolution Hi-C maps from human Fetal Brain cells. Contacts were calculated up to 30 bins distance each way from the point of interest. Top to bottom: a Jbrowse (Skinner et al., 2009) screenshot with genes and interaction profile representation (points of interest in green, their contact predictions in yellow); HiCEnterprise interaction profile plot with intensities (weighted by distance) and −log10 of FDR corrected p-values (q-values) with a threshold set at 0.01. (B) TADs, here HiCEnterprise visualization for 150 kb resolution Hi-C map of 17th chromosome from HUVEC. Left upper trianle: original Hi-C map contact frequencies; right lower triangle: −log10 of q-values of the interdomain interactions calculated with hypergeometric distribution.