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In vitro P-glycoprotein activity does not completely explain in vivo efficacy of novel centrally effective oxime acetylcholinesterase reactivators

机译：体外P-糖蛋白活性在新型中央有效的肟乙酰胆碱酯酶酶反应器的体内疗效中不完全解释

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Mary Beth Dail; Edward Caldwell Meek; Howard Wayne Chambers; Janice Elaine Chambers;
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1. In vitro P-glycoprotein activity does not completely explain in vivo efficacy of novel centrally effective oxime acetylcholinesterase reactivators [J] . Mary Beth Dail, Edward Caldwell Meek, Howard Wayne Chambers Drug and Chemical Toxicology . 2019,第1a6期

机译：体外P-糖蛋白活性并不能完全解释新型中央有效的肟乙酰胆碱酯酶蛋白反应器的体内疗效
2. A comparison of the efficacy of a bispyridinium oxime--1,4-bis-(2-hydroxyiminomethylpyridinium) butane dibromide and currently used oximes to reactivate sarin, tabun or cyclosarin-inhibited acetylcholinesterase by in vitro methods. [J] . Kuca K, Cabal J, Kassa J Die Pharmazie . 2004,第10期

机译：通过体外方法比较双吡啶肟-1,4-双-（2-羟基亚氨基甲基吡啶）丁烷二溴化物与目前使用的肟重活化沙林，塔宾或环沙蛋白抑制的乙酰胆碱酯酶的功效。
3. Novel acetylcholinesterase reactivator--oxime K048--reactivation activity in vitro. [J] . Kuca K, Marek J, Karasova J, Medicinal chemistry . 2010,第1期

机译：新型乙酰胆碱酯酶活化剂-肟K048的体外活化活性。
4. Reactivation of organophosphorus-inhibited human erythrocyte-acetylcholinesterase by oximes in vitro [C] . F. Worek, R. Widmann, O. Knopff, NATO advanced research workshop on antidotes, protectors and decorporators-a new approach in the area of disarmament: From military towards environmental purpose . 1999

机译：通过肟在体外再激活有机磷抑制的人红细胞 - 乙酰胆碱酯酶
5. In vivo efficacy of eight new bisquaternary K-oximes in comparison to 2-PAM and obidoxime against rat with paraoxon and DFP intoxication [D] . Nurulain, Syed Muhammad. 2010

机译：与2-PAM和Oboboxime相比，八种新的双季K-肟对大鼠对氧磷和DFP中毒的体内功效
6. Reactivation of Human Acetylcholinesterase and Butyrylcholinesterase Inhibited by Leptophos-Oxon with Different Oxime Reactivators in Vitro [O] . Daniel Jun, Lucie Musilova, Miroslav Pohanka, 2010

机译：Leptophos-Oxon抑制人乙酰胆碱酯酶和丁酰胆碱酯酶与不同肟复活剂的体外复活
7. A Comparison of the Potency of the Oxime HLö-7 and Currently Used Oximes (HI-6, Pralidoxime, Obidoxime) to Reactivate Nerve Agent-Inhibited Rat Brain Acetylcholinesterase by in vitro Methods [O] . Kamil Kuča, Jiří Cabal, Jiří Kassa, 2005

机译：肟Hlö-7和当前使用的肟（Hi-6，Prealoxime，Obidoxime）的效力比较重新激活神经剂抑制的大鼠脑乙酰胆碱酯酶的体外方法
8. In Search of an Effective in vivo Reactivator for Organophosphorus Nerve Agent-Inhibited Acetylcholinesterase in the Central Nervous System. [R] . Shih, T., Koplovitz, I., Kan, R. K., 2012

机译：寻找有效的体内反应激活剂有机磷神经剂抑制中枢神经系统乙酰胆碱酯酶。

In vitro P-glycoprotein activity does not completely explain in vivo efficacy of novel centrally effective oxime acetylcholinesterase reactivators

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