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Treatment-emergent neuroendocrine prostate cancer with a germline BRCA2 mutation: identification of a candidate reversion mutation associated with platinum/PARP-inhibitor resistance

机译：治疗新芽的神经内分泌前列腺前列腺癌与种系BRCA2突变：鉴定铂/ PARP抑制剂抗性相关的候选回归突变

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Deep Pandya; Myra Shah; Fuat Kaplan; Candice Martino; Gillian Levy; Mia Kazanjian; Stephen Batter; John Martignetti; Richard C. Frank;
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1. Acquired multiple secondary BRCA2 mutations upon PARPi resistance in a metastatic pancreatic cancer patient harboring a BRCA2 germline mutation [J] . Haitao Tao, Sisi Liu, Di Huang, American Journal of Translational Research . 2020,第2期

机译：在涉及BRCA2种系突变的转移性胰腺癌患者中获得多次次级BRCA2突变。患有BRCA2种系突变的转移性胰腺癌患者
2. A first Japanese case of neuroendocrine prostate cancer accompanied by lung and brain metastasis with somatic and germline BRCA2 mutation [J] . Kosaka Takeo, Hongo Hiroshi, Aimono Eriko, Pathology International . 2019,第12期

机译：第一个日本病例的神经内分泌前列腺癌伴有肺和脑转移，具有细胞和种系BRCA2突变
3. BRCA1 and BRCA2 germline mutations in Uruguayan breast and breast-ovarian cancer families. Identification of novel mutations and unclassified variants. [J] . Delgado L, Fernandez G, Grotiuz G, Breast cancer research and treatment. . 2011,第1期

机译：乌拉圭乳腺癌和乳腺癌-卵巢癌家庭的BRCA1和BRCA2种系突变。鉴定新型突变和未分类的变体。
4. GERMLINE AND SOMATIC MUTATIONS OF APC GENE AND THE GENOTYPE-PHENOTYPE ANALYSIS IN FAP AND SPORADIC COLORECTAL CANCERS [C] . Xiaorong Liu, Department of Genetics, Xiangnian Shan, 第四届国际后基因组生命科学技术学术论坛 . 2006

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5. Men's perspectives on breast cancer susceptibility gene 2 (BRCA2) mutation and prostate cancer. [D] . Cole Rodriguez, Cindy. 2015

机译：男性对乳腺癌易感基因2（BRCA2）突变和前列腺癌的看法。
6. Acquired Resistance to Poly (ADP-ribose) Polymerase Inhibitor Olaparib inBRCA2-Associated Prostate Cancer Resulting From Biallelic BRCA2 Reversion Mutations Restores Both Germline and Somatic Loss-of-Function Mutations [O] . BA Carneiro, KA Collier, RJ Nagy, -1

机译：获得性抗聚（ADP-核糖）聚合酶抑制剂Olaparib在双等位基因BRCA2回复突变导致的BRCA2相关前列腺癌恢复了生殖细胞和体细胞功能丧失突变。
7. A first Japanese case of neuroendocrine prostate cancer accompanied by lung and brain metastasis with somatic and germline BRCA2 mutation [O] . Takeo Kosaka, Hiroshi Hongo, Eriko Aimono, 2019

机译：第一个日本病例的神经内分泌前列腺癌伴有肺和脑转移，具有细胞和种系BRCA2突变

Treatment-emergent neuroendocrine prostate cancer with a germline BRCA2 mutation: identification of a candidate reversion mutation associated with platinum/PARP-inhibitor resistance

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