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Schedule feasibility and workflow for additive manufacturing of titanium plates for cranioplasty in canine skull tumors

机译:在犬头骨肿瘤中的颅骨成形术中钛板添加剂和工作流程

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摘要

Abstract Background Additive manufacturing has allowed for the creation of a patient-specific custom solution that can resolve many of the limitations previously reported for canine cranioplasty. The purpose of this pilot study was to determine the schedule feasibility and workflow in manufacturing patient-specific titanium implants for canines undergoing cranioplasty immediately following craniectomy. Results Computed tomography scans from patients with tumors of the skull were considered and 3 cases were selected. Images were imported into a DICOM image processing software and tumor margins were determined based on agreement between a board-certified veterinary radiologist and veterinary surgical oncologist. Virtual surgical planning was performed and a bone safety margin was selected. A defect was created to simulate the planned intraoperative defect. Stereolithography format files of the skulls were then imported into a plate design software. In collaboration with a medical solution centre, a custom titanium plate was designed with the input of an applications engineer and veterinary surgery oncologist. Plates were printed in titanium and post-processed at the solution centre. Total planning time was approximately 2 h with a manufacturing time of 2 weeks. Conclusions Based on the findings of this study, with access to an advanced 3D metal printing medical solution centre that can provide advanced software and printing, patient-specific additive manufactured titanium implants can be planned, created, processed, shipped and sterilized for patient use within a 3-week turnaround.
机译:摘要背景添加剂制造已经允许创建患者特异性定制解决方案,该解决方案可以解决犬颅骨成形术报告的许多限制。该试点研究的目的是确定在颅骨切除术后立即接受颅骨成形术治疗患者特异性钛植入物的时间表可行性和工作流程。结果考虑了颅骨肿瘤患者的计算断层扫描扫描,选择了3例。图像进口到DICOM图像处理软件中,基于董事会认证的兽医放射科医师和兽医手术肿瘤学家之间的协议确定了肿瘤边距。进行虚拟手术规划,选择骨骼安全保证金。创建缺陷以模拟计划的术中缺陷。然后将头骨的立体光刻格式文件导入板设计软件。与医疗解决方案中心合作,设计了一种自定义钛板,设计了应用工程师和兽医手术肿瘤科学家的输入。在钛中印刷平板并在溶液中心进行后处理。总规划时间约为2小时,制造时间为2周。结论基于本研究的调查结果,可以访问先进的3D金属印刷医疗解决方案中心,可以提供先进的软件和印刷,患者特异性添加剂制造的钛植入物可以在患者内部进行,创建,加工,运输和灭菌。一个3周的周转。

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