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Postponing intubation in spontaneously breathing major trauma patients upon emergency room admission does not impair outcome

机译:在急诊室入学时推迟在自发呼吸主要创伤患者的插管并不损害结果

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摘要

Abstract Background Pre-hospital emergency anaesthesia and tracheal intubation are life-saving interventions in trauma patients. However, there is evidence suggesting that the risks associated with both procedures outweigh the benefits. Thus, we assessed whether induction of anaesthesia and tracheal intubation of trauma patients can be postponed in spontaneously breathing patients until emergency room (ER) admission without increasing mortality. Methods Retrospective analysis of major trauma patients either intubated on-scene by an emergency medical service (EMS) physician (pre-hospital intubation, PHI) or within the first 10 min after admission at a level 1 trauma centre (emergency room intubation, ERI). Data was extracted from the German Trauma Registry, hospital patient data management and electronic clinical information system. Results From a total of 946 major trauma cases documented between 2010 and 2017, 294 patients matched the study inclusion criteria. Mortality rate of PHI (N = 258) vs. ERI (N = 36) patients was 26.4% vs. 16.7% (p = 0.3). After exclusion of patients with severe traumatic brain injury and/or pre-hospital cardiac arrest, mortality rate of PHI (N = 100) vs. ERI patients (N = 29) was 6% vs. 17.2%, (p = 0.07). Median on-scene time was significantly (p < 0.01) longer in PHI (30 min; IQR: 21–40) vs. ERI patients (20 min; IQR: 15–28). Conclusions There was no statistical difference in mortality rates of spontaneously breathing trauma patients intubated on-scene when compared with patients intubated immediately after hospital admission. Due to the retrospective study design and small case number, further studies evaluating the impact of airway management timing in sufficiently breathing trauma patients are warranted.
机译:摘要背景院前急诊麻醉和气管插管是创伤患者的救生干预措施。但是,有证据表明与两种程序相关的风险超过了福利。因此,我们评估了创伤患者麻醉和气管插管的诱导是否可以在自发的呼吸患者中推迟到急诊室(ER)入院,而不会增加死亡率。方法对主要创伤患者的回顾性分析,要么通过紧急医疗服务(EMS)医生(院前插管,PHI)或在1级创伤中心入院后的前10分钟内(急诊室插管,ERI),其次回顾性分析。数据是从德国创伤登记处提取的,医院患者数据管理和电子临床信息系统中提取。结果来自2010年至2017年至2017年至2017年之间的946个主要创伤病例,294例患者符合研究纳入标准。 PHI的死亡率(n = 258)与ERI(n = 36)患者为26.4%vs.16.7%(p = 0.3)。排除严重创伤性脑损伤和/或医院前心脏骤停的患者后,PHI的死亡率(n = 100)与ERI患者(n = 29)为6%,p <17.2%(P = 0.07)。 PHI中的中位数时间是显着的(P <0.01)(30分钟; IQR:21-40)与ERI患者(20分钟; IQR:15-28)。结论与医院入院后立即插入的患者相比,在现场插管的自发性呼吸抑郁症患者的死亡率差异没有统计学差异。由于回顾性研究设计和小案例数量,有必要进一步研究评估呼吸道管理时机充分呼吸的创伤患者的影响。

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