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Discovery of a Highly Potent, Orally Active Mitosis/Angiogenesis Inhibitor R1530 for the Treatment of Solid Tumors

机译：发现高效，口服有丝分裂/血管生成抑制剂R1530，用于治疗实体肿瘤

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Jin-Jun Liu; Brian Higgins; Grace Ju; Kenneth Kolinsky; Kin-Chun Luk; Kathryn Packman; Giacomo Pizzolato; Yi Ren; Kshitij Thakkar; Christian Tovar; Zhuming Zhang; Peter M. Wovkulich;
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1. Discovery of a Highly Potent, Orally Active Mitosis/Angiogenesis Inhibitor R1530 for the Treatment of Solid Tumors [J] . Jin-Jun Liu, Brian Higgins, Grace Ju ACS medicinal chemistry letters . 2013,第2期

机译：发现一种用于治疗实体瘤的高效，口服活性有丝分裂/血管生成抑制剂R1530
2. Discovery of a Novel, Highly Potent, and Selective Thieno[3,2-d]pyrimidinone-Based Cdc7 Inhibitor with a Quinuclidine Moiety (TAK-931) as an Orally Active Investigational Antitumor Agent [J] . Kurasawa Osamu, Miyazaki Tohru, Homma Misaki, Journal of Medicinal Chemistry . 2020,第3期

机译：用奎诺霉素部分（TAK-931）作为口服活性研究抗肿瘤剂的新型，高效和选择性噻吩并[3,2-D]嘧啶酮的CDC7抑制剂
3. Discovery of a Novel Class of Potent Coumarin Monoamine Oxidase B Inhibitors: Development and Biopharmacological Profiling of 7-[(3-Chlorobenzyl)oxy]-4-[(methylamino)methyl]-2H-chromen-2-one Methanesulfonate (NW-1772) as a Highly Potent, Selective, Reversible, and Orally Active Monoamine Oxidase B Inhibitor [J] . Pisani L, Muncipinto G, Miscioscia TF, Journal of Medicinal Chemistry . 2009,第21期

机译：一类新型强力香豆素单胺氧化酶B抑制剂的发现：7-[（3-氯苄基）氧基] -4-[（甲基氨基）甲基] -2H-铬-2-酮甲烷磺酸盐（NW-1772）的开发和生物药理学分析）作为高效，选择性，可逆和口服活性单胺氧化酶B抑制剂
4. EGFRvIII T-Cell TandAbs Are Specific and Highly Potent Drug Candidates for the Treatment of a Variety of Solid Tumors [C] . Kristina Ellwanger, Uwe Reusch, Ivica Fucek, PEGS . 2014

机译：EGFRVIII T细胞Tandabs是针对治疗各种实体瘤的特异性和高效的药物候选者
5. Discovery of a small molecule dihydroquinolinone inhibitor with potent antiproliferative and antitumor activity results in catastrophic cell division. [D] . Christadore, Lisa M. 2013

机译：发现具有有效的抗增殖和抗肿瘤活性的小分子二氢喹啉酮抑制剂会导致灾难性的细胞分裂。
6. Discovery of a HighlyPotent Orally Active Mitosis/Angiogenesis Inhibitor R1530 for theTreatment of Solid Tumors [O] . Jin-Jun Liu, *, Brian Higgins, 2013

机译：发现高度强力口服活性有丝分裂/血管生成抑制剂R1530实体瘤的治疗
7. Discovery of a Novel, Highly Potent, and Selective Thieno3,2dpyrimidinone-Based Cdc7 Inhibitor with a Quinuclidine Moiety (TAK-931) as an Orally Active Investigational Antitumor Agent [O] . -1

机译：用奎诺霉素部分（TAK-931）作为口服活性研究抗肿瘤剂的新型，高效和选择性噻吩并3,2d嘧啶酮基CDC7抑制剂

Discovery of a Highly Potent, Orally Active Mitosis/Angiogenesis Inhibitor R1530 for the Treatment of Solid Tumors

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