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In Vitro and In Vivo Drug-Drug Interaction Studies to Assess the Effect of Abiraterone Acetate, Abiraterone, and Metabolites of Abiraterone on CYP2C8 Activity

机译：体外和体内药物 - 药物的相互作用研究，评估AbiraTerone乙酸酯，AbiraTerOne和Abiraaterone代谢物对CYP2C8活性的影响

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J. Monbaliu; M. Gonzalez; A. Bernard; J. Jiao; C. Sensenhauser; J. Snoeys; H. Stieltjes; I. Wynant; J. W. Smit; C. Chien;
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1. In Vitro and In Vivo Drug-Drug Interaction Studies to Assess the Effect of Abiraterone Acetate, Abiraterone, and Metabolites of Abiraterone on CYP2C8 Activity [J] . Monbaliu, Johan, Gonzalez, Martha, Bernard, Apexa, Drug Metabolism and Disposition: The Biological Fate of Chemicals . 2016,第10期

机译：评估醋酸阿比特龙，阿比特龙和阿比特龙代谢物对CYP2C8活性的影响的体外和体内药物相互作用研究
2. Rapid conversion of the ester prodrug abiraterone acetate results in intestinal supersaturation and enhanced absorption of abiraterone: In vitro, rat in situ and human in vivo studies [J] . Stappaerts Jef, Geboers Sophie, Snoeys Jan, European journal of pharmaceutics and biopharmaceutics: official journal of Arbeitsgemeinschaft fuer Pharmazeutische Verfahrenstechnik e.V . 2015,第Null期

机译：酯前药物的快速转化乙酸酯导致肠道过饱和和增强AbiraTerone的吸收：体外，大鼠的体内研究
3. The role of drug-drug interactions in prostate cancer treatment: Focus on abiraterone acetate/prednisone and enzalutamide [J] . Del Re Marzia, Fogli Stefano, Derosa Lisa, Cancer Treatment Reviews . 2017,第期

机译：药物 - 药物相互作用在前列腺癌治疗中的作用：专注于AbiraTerone醋酸盐/泼尼松和依甲醛酰胺
4. A novel validated liquid chromatographic-tandem mass spectroscopy method for the quantification of abiraterone acetate and abiraterone in human plasma [C] . Vanessa Martins, Yasmin Asad, Nicola Wilsher, ASMS Conference on Mass Spectrometry and Allied Topics . 2006

机译：一种新型验证的液相色谱 - 串联质谱法，用于量子血浆中Abiraatorone乙酸酯和Abiraatorons的定量
5. Improvement of gastroparesis management by addressing challenges in drug metabolism: Studies with metabolite identification, reaction phenotyping and in vitro drug-drug interactions. [D] . Youssef, Amir S. 2013

机译：通过应对药物代谢方面的挑战来改善胃轻瘫的管理：有关代谢物鉴定，反应表型和体外药物相互作用的研究。
6. Abiraterone acetate plus LHRH therapy versus abiraterone acetate while sparing LHRH therapy in patients with progressive metastatic and chemotherapy-naïve castration-resistant prostate cancer (SPARE): study protocol for a randomized controlled trial [O] . Carsten-Henning Ohlmann, Michelle Jäschke, Peter Jaehnig, 2017

机译：醋酸阿比特龙联合LHRH治疗与醋酸阿比特龙同时保留LHRH治疗在进行性转移性和未接受去势的前列腺癌（SPARE）患者中的研究：一项随机对照试验的研究方案
7. Rapid conversion of the ester prodrug abiraterone acetate results in intestinal supersaturation and enhanced absorption of abiraterone: In vitro, rat in situ and human in vivo studies [O] . Stappaerts Jef, Geboers Sophie, Snoeys Jan, 2015

机译：酯前药乙酸阿比特龙酯的快速转化导致肠道过饱和并增加阿比特龙的吸收：体外，原位大鼠和人体体内研究

In Vitro and In Vivo Drug-Drug Interaction Studies to Assess the Effect of Abiraterone Acetate, Abiraterone, and Metabolites of Abiraterone on CYP2C8 Activity

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