Standard Reference Materials for Chemical and Biological Studies of Complex Environmental Samples

摘要

Standard Reference Materials (SRM's) from the National Institute of Standards and Technology (NIST) are often used in methods development and inter-laboratory comparison studies since they are homogeneous and readily available to the scientific community. SRM 1649 (Urban Dust/Organics), SRM 1650 (Diesel Particulate Matter), and SRM 1597 (Complex Mixture of Polycyclic Aromatic Hydrocarbons from Coal Tar) are three environmental samples which have been used by the scientific community for this purpose. The SRM's were originally developed to assist laboratories in validating analytical procedures for the determination of polycyclic organic compounds in complex mixtures. In addition, the SRM's have been valuable for the comparison of methodologies for bacterial bioassays and the development of bioassay-directed fractionation and bioassay directed chemical analysis techniques. Most recently the SRM's were chosen for use as test samples in a collaborative study coordinated by the World Health Organization-International Program on Chemical Safety. The paper provides a summary of much of the work to date (published and unpublished) on the chemical and biological characterization of the three SRM's. Information regarding the availability of other NIST SRM's that might be useful for these types of studies will be provided also. (Copyright (c) 1992 Elsevier Science Publishers B.V.)