Cystic Fibrosis and DNA Tests: Implications of Carrier Screening

摘要

The report gathers technical information on diagnosis (especially concerning oneparticular mutation associated with approximately 70% of all cystic fibrosis cases) and on treatment; examines prospects for DNA tests to detect additional cystic fibrosis mutations; analyzes legal, ethical, and economic issues of population screening for cystic fibrosis; surveys genetic counselors for their opinions and attitudes toward population screening for cystic fibrosis; and surveys commercial health insurers and health maintenance organizations to assess attitudes.