Behavioral Development Following Daily Episodes of Mother-Infant Separation in the Rat.

摘要

Sprague-Dawley rat pups were either maternally deprived in warm incubators for 6 hours each day or left alone with their dams, and then tested on a range of endpoints commonly used in developmental neurotoxicity. These included motor activity, olfactory learning and retention, T-maze delayed alternation, acoustic startle response, and auditory thresholds. Interrupting the mother-infant interaction for 6 hours/day had little or no effect by itself on growth and behavioral development.