Detection of Direct-Acting Mutagens in Ambient Air: A Comparison of Two HighlySensitive Mutagenicity Assays

摘要

Ambient air has been shown to contain numerous hazardous pollutants, many ofwhich are known or suspected carcinogens and mutagens. Bioassays play a prominent role in the characterization of these genotoxic pollutants, and as new test methods are developed, it is incumbent upon researchers to evaluate assay performance and report relative merits. In the study, two Salmonella test methods (the spiral and preincubation assays) were assessed to determine their usefulness as screening methods for monitoring direct-acting mutagens in ambient air. (Copyright (c) 1992 Wiley-Liss, Inc.).