Quality of Life and Seizures After Epilepsy Surgery. Executive Summary, Final Report and Appendices

摘要

Longitudinal health-related quality of life (HRQOL) and seizure data on 248 consecutive patients who underwent evaluation for surgery for intractable epilepsy were analyzed. (1) HRQOL of post-surgical epilepsy patients who became seizure free was better than that of patients with hypertension, diabetes, heart disease, or depressive symptoms; patients who continued to have seizures scored worse on mental health measures compared to all groups. (2) Mood adjective checklist score improved on 7 of 8 scales after epilepsy surgery. (3) The relationships of previously published seizure-focused surgery outcome classification systems modified to derive new ones that were more reflective of HRQOL. (4) Finally, patients who underwent surgery had much better seizure outcomes at an average follow-up of six years than nonsurgical patients.