NIOSH Posthearing Comments from the National Institute for Occupational Safetyand Health on the Occupational Safety and Health Administration Proposed Rule on Occupational Exposure to Methylene Chloride by J. D. Millar, January 14, 1993

摘要

This testimony summarizes information provided to clarify earlier testimonyrelated to methylene chloride (75092) exposures. An error made in earlier testimony concerning confidence interval determination is discussed. During a study on methylene chloride exposure in rats, nervous system damage was recorded, but this cannot be extrapolated to help predict the effects of shorter exposure at lower concentration in humans. With regard to questions concerning the effects of carbon monoxide (630080) on human and animal performance reported in various studies, NIOSH was not able to offer any further clarification of the issue.