Workshop Report on Developmental Neurotoxic Effects Associated with Exposure to PCBs. Held in Research Triangle Park, North Carolina on September 14-15, 1992

摘要

The report summarizes the outcome of the PCB Developmental Neurotoxicity Workshop in relation to the stated goals of the workshop. The first goal was to address the question of whether currently available data are sufficient for risk assessment. Based on an evaluation of the strengths and weaknesses in the data and on the consistency of effects seen in all species tested, including humans, there is sufficient information to indicate that PCBs cause developmental neurotoxicity. The second goal of the workshop was to identify any additional information that might be used to support the developmental neurotoxicity data in risk assessment. The third goal of the workshop was to recommend research needed to address risk assessment issues. The overwhelming sense of the meeting was that there is a need for more research on the developmental effects of PCBs.