Transport, Transformation and Fate Endocrine Disruptors: Potential Areas ofExposure Research

摘要

A growing number of studies suggest that several persistant organic pollutants(POPs) and some organic forms of heavy metals, such as those listed recently by the Inter-Organizational Program for the Sound Management of Chemicals, appear to mimic or to disrupt hormonal mechanisms in humans and wildlife. EPA is exploring methods and models to measure and to predict exposure to these substances. This paper addresses a number of approaches the Agency may take to conduct exposure research of endocrine disrupting compounds within the Agency's risk assessment framework.