Process Models of Enzymatic Enantioselective Conversion of Poorly Water SolubleSolids Suspended in Water or Dissolved in Water-Cosolvent Mixture

摘要

;Contents: Introduction and outline of the thesis; Enzymatic resolution ofracemates contaminated by racemic product; Solvent induced change of enzyme enantioselectivity: Rule or exception; Simple dissolution-reaction model for enzymatic conversion of suspension of solid substrate; Understanding the influence of temperature change and cosolvent addition on the converson rate of enzymatic suspension reactions based on regime analysis; Potential of enzymatic kinetic resolution using solid substrates suspension: Improved yield, productivity, substrate concentration and recovery; Summary; and Acknowledgments.