Effects of Stress Response on Wound Healing.

摘要

The cumulative physiologic effects of psychological, physical and surgical stress result in hypothalamic-pituitary-adrenal (HPA) mediated peripheral vasoconstriction and elevated serum cortisol levels, both of which have been implicated in wound healing. The purpose of this study was to describe the affects of both preoperative and postoperative psychological stress and minor and moderate surgical stress on wound healing in the hope of gaining insight into what characteristics within individuals are most likely to equate with efficient would healing.