Final Report on Carcinogens Background Document for Dyes Metabolized to 3,3'-Dimethylbenzidine.

摘要

Dyes metabolized to 3,3'-dimethylbenzidine (dimethylbenzidine dyes as a class) were nominated for listing in the Report on Carcinogens (RoC) by the National Institute of Environmental Health Sciences (NIEHS) RoC Review Group (RG1) based on the current RoC listing of the parent compound 3,3?-dimethylbenzidine (DMB) as reasonably anticipated to be a human carcinogen and the fact that the azo linkages of DMB-based dyes are chemically equivalent and are readily cleaved by chemical or enzymatic reduction to form free DMB and the chromophore(s).