Synchrotron Radiation for Macromolecular Crystallography: Report of the Office of211 Science and Technology Policy, Working Group on Structural Biology at Synchrotron 211 Radiation Facilities

摘要

There have been numerous demonstrations of the advantages of using synchrotron211u001eradiation for crystallography: rapid data collection, use of smaller crystals 211u001ethan with conventional x-ray sources, and the ability to conduct measurements at 211u001emultiple wavelengths. Because of these characteristics, the demand on the 211u001eavailable synchrotron radiation increased from 18 percent in 1990 to 44 percent 211u001ein 1996. The demand for synchrotron access is likely to increase even more 211u001erapidly in tandem with developments in genomics, where the discovery of new 211u001eproteins will provide new opportunities for understanding protein structure and 211u001efunction.