Relative Bioavailability of Arsenic in Soils from the VB170 Site.

摘要

The gastrointestinal absorption of arsenic from soil samples collected from residential properties at the Vasquez Boulevard and I-70 (VBI70) Superfund site was measured using young swine. Test materials include composite soil samples from five different residences with arsenic levels ranging from 290 to 860 ppm. In addition, one sample was prepared by mixing clean site soil (arsenic less than 10 ppm) with an arsenical herbicide (PAX) to yield a concentration of about 460 ppm. Groups of animals (four animals per dose group) were given oral doses of reference material (sodium arsenate) or test material twice a day for 12 days. Urine excreted by each animal was collected on days 6-7, 8-9 and 10-11. The urinary excretion fraction (UEF) (the ratio of the amount excreted per 48 hours divided by the dose given per 48 hours) was calculated for each test material using linear regression analysis.