Pharmacologic Management of Heart Failure and Left Ventricular Systolic Dysfunction: Effect in Female, Black, and Diabetic Patients, and Cost-Effectiveness. Evidence Report/Technology Assessment Number 82

摘要

This evidence-based report had two objectives. The first objective was to assess whether angiotensin-converting enzyme inhibitors (ACE inhibitors) and beta-adrenergic blocking agents (beta-blockers) are effective in patients with left ventricular systolic heart failure and whether this effectiveness differs in the following subpopulations: men, women, blacks, whites, diabetics, and nondiabetics. The second objective was to assess the cost-effectiveness of both treatment of and screening for left ventricular systolic dysfunction.