Methods of Treating Disease through the Administration of a Manzamine Analog or Derivative.

摘要

A method of treating cancer, inflammatory disease or an infectious disease or condition in a subject in need of such treatment is disclosed. The method comprises administering to a subject and effective amount of a manzamine, or a optical isomer or racemate or tautomer thereof or a pharmaceutically acceptable salt or prodrug thereof generated through optimized fermentation of a 'Micromonospora' sp, extraction from sponges and then modified through semi-synthesis.