Protein Biomarkers and Therapeutic Targets in an Animal Model for Amyotrophic Lateral Sclerosis.

摘要

The invention provides a method for determining the onset and/or progression of ALS in an animal. The method comprises (a) obtaining a sample from the animal, (b) analyzing the proteins in the sample by mass spectroscopy, and (c) determining a mass spectral profile for the sample. The invention also provides isolated protein biomarkers of ALS.