Urate Oxidase (PAT-APPL-11-357 028).

机译：尿酸氧化酶（paT-appL-11-357 028）。

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摘要

The present invention relates, in general, to urate oxidase (uricase) proteins and nucleic acid molecules encoding same. In particular, the invention relates to uricase proteins which are particularly useful as, for example, intermediates for making improved modified uricase proteins with reduced immunogenicity and increased bioavailability.

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Hershfield, M.; Kelly, S. J.;
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年度 2006
页码 1-42
总页数 42
原文格式 PDF
正文语种 eng
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关键词
Urate oxidase; Proteins; Nucleic acids; Patent applications; Molecular biology; Immunity; Biodegradation;

机译：尿酸氧化酶;蛋白质;核酸;专利申请;分子生物学;免疫学;生物降解;

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专利

1. Purine-induced expression of urate oxidase and enzyme activity in Atlantic salmon (Salmo salar) - Cloning of urate oxidase liver cDNA from three teleost species and the African lungfish Protopterus annectens [J] . Andersen O, Aas TS, Skugor S, The FEBS journal . 2006,第13期

机译：嘌呤诱导的大西洋鲑鱼（Salmo salar）中尿酸氧化酶的表达和酶活性-三种硬骨鱼和非洲肺鱼Protopterus annectens尿酸氧化酶肝脏cDNA的克隆
2. A biohybrid hydrogel for the urate-responsive release of urate oxidase [J] . Geraths C., Daoud-El Baba M., Charpin-El Hamri G., Journal of Controlled Release: Official Journal of the Controlled Release Society . 2013,第1期

机译：生物复合水凝胶，用于尿酸盐响应释放尿酸盐氧化酶
3. Disrupted and transgenic urate oxidase alter urate and dopaminergic neurodegeneration [J] . Xiqun Chen, Thomas C. Burdett, Cody A. Desjardins, Proceedings of the National Academy of Sciences of the United States of America . 2013,第1期

机译：破裂的转基因尿酸盐氧化酶改变尿酸盐和多巴胺能神经变性
4. Cloning and expression of urate oxidase and its application in serumuric acid analysis [C] . The Seventh China-Japan joint symposium on enzyme engineering . 2002

机译：尿酸氧化酶的克隆，表达及其在血清尿酸分析中的应用
5. The effect of alpha-aminoadipate delta-semialdehyde synthase knockdown on the lysine requirement and urate oxidase knockdown on oxidative stress in a murine hepatic cell line. [D] . Cleveland, Beth Marie. 2007

机译：鼠肝细胞系中α-氨基己二酸δ-半醛合酶敲除对赖氨酸需求的影响，尿酸氧化酶敲除对氧化应激的影响。
6. An Optical Urate Biosensor Based on Urate Oxidase and Long-Lifetime Metalloporphyrins [O] . Tokunbo Falohun, Michael J. McShane 2020

机译：基于尿酸盐氧化酶和长寿命金属卟啉的光学尿酸盐生物传感器
7. An Optical Urate Biosensor Based on Urate Oxidase and Long-Lifetime Metalloporphyrins [O] . Tokunbo Falohun, Michael J. McShane 2020

机译：基于尿酸氧化酶和长寿命金属卟啉的光尿生物传感器

Urate Oxidase (PAT-APPL-11-357 028).

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