In utero and Early Postnatal Exposure to Arsenic May Alter Pulmonary Function.

摘要

Growth and development require the expression of genes and gene products to be temporally and spatially coordinated. text box stating: Research indicates that exposure to high arsenic concentrations in adults can result in lung cancer and/or chronic lung disease. In utero and early postnatal exposure to toxicants can affect gene expression, which can alter organ structure and physiological function. University of Arizona (UA) SBRP investigator, Dr. Clark Lantz, and his research team believe that in utero and postnatal arsenic exposure via drinking water, at environmentally relevant doses, can result in altered gene expression. These alterations in gene expression may impact lung and blood vessel development, resulting in chronic disease as an adult.