The Effect of Eserine and Gammexane on the Absolutely and Relatively Refractory Period of Turtle Heart Strips and the Effect of Gammexane on the Spontaneously Beating Frog Heart and (Technical Report No. l.), (A Study of the Effects of the Neutral Alkaloi

摘要

The work done under this contract can be roughly divided into 4 phases.nThe first phase stems from the observation that the length of the absolute refractory period governs the magnitude of the twitch to tension ration of skeletal muscle at any temperature (Ramsey Street 1).nThe second phase involved the determination of the effect of temperature on the maximal titanic tension developed by single muscle fibers of the frog.nThe third phase was the development of a rather comprehensive hypothesis or analysis of muscle that satisfactorily encompassed the mechanical data of muscle such as length-tension diagram, force-velocity relationships, maximum changes in length as well as most of the exchanges of teat and work.nThe fourth phase may be entitled “An investigation if contractures caused by chemical agents particularly ryanodine”.