Routine human and animal blood lipoprotein analyses have been carried out in this labora¬tory since the initial training of one of us (L.J.M.) by the Gofman group in 1950. Since early 1953, the technics employed here have remained essentially as described by De Lalla and Gof¬man (2). Over the past 2-year period, there¬fore, a considerable body of data has been ac¬cumulated relative to the inherent variability of the multistep procedure when the analyses are accomplished on a routine basis. Since purified, homogeneous lipoprotein fractions are not avail¬able, recovery studies of the analytical technic could not be accomplished. It was decided, there¬fore, to organize and expand our variability data so that even if the accuracy of a result were not known, at least the limits of comparability of successive results could be estimated.
展开▼
