REACTIONS OF ORGANOPHORUS ACIDS WITH ISOCYANATES PARTⅠ- THE BASE-CATALYZED CONDENSATION

摘要

Tertiary amine salts of acids containing reactive hydrogen atoms bonded to carbon or phosphorus have been found to undergo a base-catalyzed reaction with isocyanates to yield the corresponding C-or P-carbamoyl derivatives. The acids are exemplified by phenylacetic acid and phenylphosphinic acid. The latter acid can also be converted to phenyl(phenylcarbamoyl)phosphinic acid by way of an Ivanov reac¬tion in which a salt of a P-Grignard reagent is uti¬lized. O-carbamoyl derivatives are formed by reaction of isocyanates with the half salts of dibasic acids such as phosphonic acids. Strongly acidic hydroxyl groups bonded to phosphorus do not undergo this type of reaction.