Dogs were placed in full pressure suits and helmets and exposed to pressures from 4 to 230 mm. Hg for periods ranging from 2 to 300 minutes. The measured cardiovascular alterations increased with pro¬longed exposure times. Pulmonary blood volume increased while the animal was breathing 100% oxygen at 4 to 8 mm. Hg pressure. The pulmonary blood volume began to decrease at a pressure of 140 mm. Hg. All increased pressures caused a decreased cardiac index and increased systemic resistance. The pressure suit used in these studies does not offer complete and prolonged protection to the animal exposed to compensated high breathing pressures.
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