Developmental Study Relating to the Preparation of a Respiratory Syncytial Virus Vaccine

摘要

The following studies represent the areas investigated during the past six months: Biological Studies: Adaptation and serial passages of various RS strains in different tissue culture systems; Plaque assay technique; Preparation of serological reagents; Developmental studies to improve viral yields; Development of potency assay methods in small laboratory animals; Biochemical and Biophysical Studies: Filtration studies; Concentration and Purification studies; Viral concentrates for oncogenicity testing.