Cancer Therapy by Interstitial and Intracavitary Radiation.

摘要

The biomedical program to study 'Cancer Therapy by Interstitial and Intracavitary Radiation'was divided into three identifiable areas: (a) radiation exposure; (b) radiation dosimetry;and (c) clinical trials. The specific aims of this study were for the most part satisfactorily concluded. Economic production of iodine seeds for permanent implantation became possible largely because of automation and increased production of the seeds by the manufacturers. The cost was brought down to $5 a seed,compared to $12.50 a seed,which was the cost at the initiation of this project. No other isotopes were investigated,however,for permanent implantation because of the prohibitive cost of production (e.g.,cesium-131seeds are in the order of $50per seed). The design of a special source inserter (gun) with a suitable magazine for inserting low energy sources has improved and simplified the technique of permanent interstitial implantation.